Skip to search formSkip to main contentSkip to account menu

MLH3 gene

Known as: MutL, E. COLI, HOMOLOG OF, 3, MLH3, MutL Homolog 3 Gene 
This gene plays a role in DNA mismatch repair and is associated with hereditary nonpolyposis colon cancer.
National Institutes of Health

Related topics

Related topics

5 relations
DNA RepairHereditary Nonpolyposis Colorectal CancerMLH3 protein, humanMLH3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A frameshift mutation in exon 19 of MLH1 in a Chinese Lynch syndrome family: a pedigree study
概要目的寻找一个Lynch 综合征患者所在家系携带的DNA 错配修复基因突变,探讨各突变对肿瘤发生发展 的影响创新点MLH1 的第19 号外显子c.2250_2251insAA… 
2018
2018
[Genetic variations in MLH3 and MSH2 genes are associated with the sensitivity and prognosis in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy].
  • J. YangX. Wang W. Tan
  • Zhonghua zhong liu za zhi [Chinese journal of…
  • 2018
  • Corpus ID: 49411902
Objective: To investigate the associations between genetic variations in DNA mismatch repair genes and sensitivity as well as… 
2018
2018
Abstract 4608: Immunologic and clinical implications of harboring mutations in mismatch repair (MMR) genes in non-small cell lung cancer (NSCLC)
MMR system is one of many cellular DNA repair mechanisms, verifying and maintaining repeat count of microsatellites during cell… 
2016
2016
Sequence-based association analysis identifies coding and non-coding variants in HFM1, MLH3, MSH4, MSH5, RNF212 and RNF212B with large effects on male and female recombination rate in cattle
2016
2016
HIGHER MALE THAN FEMALE RECOMBINATION RATE LARGELY CONTROLLED BY MISSENSE VARIANTS IN RNF212, MLH3, HFM1, MSH5 AND MSH4 IN CATTLE
2015
2015
بررسي وقوع ريزحذف هاي كروموزوم Y و پلي مورفيسم ژنهاي MSH5 C85T و MLH3 C2531T درمردان نابارور مبتلابه آزواسپرمي غيرانسدادي
بررسي وقوع ريزحذف هاي كروموزوم Y و پلي مورفيسم ژنهاي MSH5 C85T و MLH3 C2531T… 
2012
2012
Expression Analysis of MLH3, MLH1, and MSH4 in Maturation Arrest
The expression of DNA mismatch repair (DMMR) genes in patients with maturation arrest (MA) was analyzed. Samples were subjected… 
2006
2006
A role for Mlh 3 in somatic hypermutation
Somatic hypermutation (SHM) and class switch recombination (CSR) allow B cells to make high affinity antibodies of various… 
Review
2005
Review
2005
Molecular alterations in familial colorectal cancer
............................................................................................................ 9 REVIEW OF THE… 
2004
2004
Germline mutations of MLH3 in Korean hereditary nonpolyposis colorectal cancer
1324 The autosomal dominantly inherited form of colorectal polyposis and cancer, familial adenomatous polyposis (FAP), is in the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)