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MLH3 gene

Known as: MutL, E. COLI, HOMOLOG OF, 3, MLH3, MutL Homolog 3 Gene 
This gene plays a role in DNA mismatch repair and is associated with hereditary nonpolyposis colon cancer.
National Institutes of Health

Related topics

Related topics

5 relations
DNA RepairHereditary Nonpolyposis Colorectal CancerMLH3 protein, humanMLH3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
[Genetic variations in MLH3 and MSH2 genes are associated with the sensitivity and prognosis in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy].
  • J. YangX. Wang W. Tan
  • Zhonghua zhong liu za zhi [Chinese journal of…
  • 2018
  • Corpus ID: 49411902
Objective: To investigate the associations between genetic variations in DNA mismatch repair genes and sensitivity as well as… 
2016
2016
Sequence-based association analysis identifies coding and non-coding variants in HFM1, MLH3, MSH4, MSH5, RNF212 and RNF212B with large effects on male and female recombination rate in cattle
2015
2015
Single-nucleotide polymorphism rs 175080 in the MLH3 gene and its relation to male infertility
PurposeMLH3, a MutL homolog protein in mammals playing a role in DNA mismatch repair, is associated with spermatogenesis and male… 
2014
2014
Mismatch Repair Gene MLH3 Pro844Leu and Thr942Ile Polymorphisms and the Susceptibility to Cervical Carcinoma and HPV Infection: A Case-Control Study in a Chinese Population
To investigate the association between MLH3 Pro844Leu, Thr942Ile polymorphisms and potential linkage with the risk of cervical… 
2012
2012
Expression Analysis of MLH3, MLH1, and MSH4 in Maturation Arrest
The expression of DNA mismatch repair (DMMR) genes in patients with maturation arrest (MA) was analyzed. Samples were subjected… 
2008
2008
The first functional study of MLH3 mutations found in cancer patients
The MLH3 gene is one of the five mismatch repair (MMR) genes associated with hereditary nonpolyposis colorectal cancer (HNPCC… 
2006
2006
MLH3 mutation in endometrial cancer.
MLH3 is a recently described member of the DNA mismatch repair gene family. Based on its interaction with the MutL homologue MLH1… 
2006
2006
A role for Mlh3 in somatic hypermutation.
2006
2006
Mutation screening of mismatch repair gene Mlh3 in familial esophageal cancer.
AIM To shed light on the possible role of mismatch repair gene Mlh3 in familial esophageal cancer (FEC). METHODS A total of 66… 
2006
2006
A role for Mlh 3 in somatic hypermutation
Somatic hypermutation (SHM) and class switch recombination (CSR) allow B cells to make high affinity antibodies of various… 
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