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MLH3 protein, human

Known as: mutL homolog 3 (E. coli) protein, human, mutL homolog 3 protein, human, MLH3 
DNA mismatch repair protein Mlh3 (1453 aa, ~164 kDa) is encoded by the human MLH3 gene. This protein is involved in DNA mismatch repair.
National Institutes of Health

Related topics

Related topics

9 relations
Cell NucleusDNA RepairDNA Repair GeneDNA repair protein

Broader (1)

MutL Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Gene mapping and molecular analysis of hereditarynon-polyposis colorectal cancer (Lynch Syndrome)using systems biological approaches
Hereditary non-polyposis colorectal cancer (HNPCC) also known as Lynch Syndrome (LS), is a hereditary form of colorectal cancer… 
2018
2018
[Genetic variations in MLH3 and MSH2 genes are associated with the sensitivity and prognosis in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy].
  • J. YangX. Wang W. Tan
  • Zhonghua zhong liu za zhi [Chinese journal of…
  • 2018
  • Corpus ID: 49411902
Objective: To investigate the associations between genetic variations in DNA mismatch repair genes and sensitivity as well as… 
2013
2013
بررسی فراوانی پلی مورفیسم C2531T در ژن MLH3 در مردان نابارور مبتلا به آزواسپرمی یا الیگواسپرمی شدید و بدون علت
2012
2012
Expression Analysis of MLH3, MLH1, and MSH4 in Maturation Arrest
The expression of DNA mismatch repair (DMMR) genes in patients with maturation arrest (MA) was analyzed. Samples were subjected… 
2008
2008
Two new MLH1 germline mutations in Brazilian lynch syndrome families
2008
2008
Kim Holloway was awarded a second year of her fellowship from the Hereditary Diseases Foundation to study the role of MLH3 in triplet repeat expansions in the germ line.
2006
2006
A role for Mlh 3 in somatic hypermutation
Somatic hypermutation (SHM) and class switch recombination (CSR) allow B cells to make high affinity antibodies of various… 
Review
2005
Review
2005
Molecular alterations in familial colorectal cancer
............................................................................................................ 9 REVIEW OF THE… 
2004
2004
Germline mutations of MLH3 in Korean hereditary nonpolyposis colorectal cancer
1324 The autosomal dominantly inherited form of colorectal polyposis and cancer, familial adenomatous polyposis (FAP), is in the… 
2000
2000
High throughput genetic screening for the detection of hereditary non-polyposis colon cancer (HNPCC) using capillary electrophoresis.
Approximately 5-10% of all colorectal carcinomas arise from cancer predisposition syndromes caused by heterozygote germline… 
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