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MK 0677

Known as: MK 677, MK-0677, MK-677 
 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Two nonpeptide (L692,429 and MK-677) and two peptide [GH-releasing peptide (GHRP)-6 and ghrelin] agonists were compared in… Expand
Highly Cited
2004
Highly Cited
2004
Objectives: To evaluate the effects of MK‐0677, an orally active growth hormone (GH) secretagogue, on functional recovery from… Expand
Highly Cited
2001
Highly Cited
2001
GH increases bone turnover and stimulates osteoblast activity. We hypothesized that administration of MK-677, an orally active GH… Expand
Highly Cited
1998
Highly Cited
1998
Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The… Expand
Highly Cited
1998
Highly Cited
1998
The reversal of diet-induced negative nitrogen balance by GH suggests a possible therapeutic role for GH treatment in catabolic… Expand
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1998
1998
The effect of 2 months of treatment with the oral growth hormone (GH) secretagogue MK‐677 on markers of bone metabolism was… Expand
Highly Cited
1997
Highly Cited
1997
Previous studies have indicated the existence of common mechanisms regulating sleep and somatotropic activity. In the present… Expand
Highly Cited
1996
Highly Cited
1996
To assess the effects of prolonged administration of a novel analog of GH-releasing peptide (MK-677), nine healthy young men… Expand
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Highly Cited
1996
Highly Cited
1996
Aging is associated with declining activity of the GH axis, possibly contributing to adverse body composition changes and… Expand
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1996
1996
MK-0677, a spiroindoline sulfonamide, is a novel, orally active GH secretagogue. The effects of MK-0677 on serum GH and other… Expand