Linkage Disequilibrium

Known as: LD, Disequilibrium, Linkage, Linkage Disequilibriums 
Nonrandom association of linked genes; the occurrence of some genes together, more often than would be expected based upon their physical separation… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2017
020040060080019632017

Papers overview

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Highly Cited
2008
Highly Cited
2008
ldne is a program with a Visual Basic interface that implements a recently developed bias correction for estimates of effective… (More)
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Highly Cited
2005
Highly Cited
2005
ABSTRACTIn multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of… (More)
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Highly Cited
2005
Highly Cited
2005
Although many algorithms exist for estimating haplotypes from genotype data, none of them take full account of both the decay of… (More)
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Highly Cited
2004
Highly Cited
2004
In this report, we describe a simple correction for multiple testing of single-nucleotide polymorphisms (SNPs) in linkage… (More)
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Highly Cited
2004
Highly Cited
2004
Common genetic polymorphisms may explain a portion of the heritable risk for common diseases. Within candidate genes, the number… (More)
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Highly Cited
2003
Highly Cited
2003
Association tests of multilocus haplotypes are of interest both in linkage disequilibrium mapping and in candidate gene studies… (More)
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Highly Cited
2001
Highly Cited
2001
With the availability of a dense genome-wide map of single nucleotide polymorphisms (SNPs), a central issue in human genetics is… (More)
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Highly Cited
1999
Highly Cited
1999
Recently, attention has focused on the use of whole-genome linkage disequilibrium (LD) studies to map common disease genes. Such… (More)
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Highly Cited
1993
Highly Cited
1993
A population association has consistently been observed between insulin-dependent diabetes mellitus (IDDM) and the "class 1… (More)
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Highly Cited
1968
Highly Cited
1968
A theoretical investigation has been made of the influence of population size (N) and recombination fraction (c) on linkage… (More)
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