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Linkage Disequilibrium

Known as: LD, Disequilibrium, Linkage, Linkage Disequilibriums 
Nonrandom association of linked genes; the occurrence of some genes together, more often than would be expected based upon their physical separation… 
National Institutes of Health

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Related topics

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Broader (1)

Chromosome Mapping
Genetic screening methodfamily geneticshuman population geneticsphysiological aspects

Papers overview

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Highly Cited
1998
Highly Cited
1998
Genetic structure of IDDM1: two separate regions in the major histocompatibility complex contribute to susceptibility or protection. Belgian Diabetes Registry.
We analyzed 11 markers in the IDDM1 region in 120 IDDM patients and 83 healthy control subjects who were fully matched for the… 
1994
1994
Isolation of CA dinucleotide repeats close to D6S105; linkage disequilibrium with haemochromatosis.
The gene for hereditary haemochromatosis (HC) is linked to HLA-A and D6S105 on chromosome 6p. Both markers have also been… 
1987
1987
Disequilibrium pattern analysis. II. Application to Danish HLA A and B locus data.
Disequilibrium pattern analysis, a general method for analyzing evolutionary events acting on pairs of tightly linked polymorphic… 
Review
1986
Review
1986
Linkage disequilibria between pairs of loci within a highly polymorphic region of chromosome 2Q.
A recently described region on chromosome 2q contains seven restriction fragment length polymorphisms (RFLPs) revealed by single… 
1986
1986
RFLP analysis of HLA-DR and -DQ genes and their linkage relationships in the Pacific.
Human genomic DNA samples from Melanesians, Micronesians, and Caucasoids of known HLA-DR type were examined with cDNA probes for… 
Highly Cited
1983
Highly Cited
1983
Restriction fragment length polymorphisms associated with immunoglobulin C gamma genes reveal linkage disequilibrium and genomic organization.
We have demonstrated that restriction fragment length polymorphisms (RFLPs) produced by BamHI can be used as markers for constant… 
1982
1982
Linkage disequilibrium between insulin-dependent diabetes and the Kidd blood group Jkb allele.
We studied 102 randomly ascertained probands from the Upper Midwest United States with insulin-dependent diabetes mellitus (IDDM… 
1980
1980
Linkage disequilibrium in isolated populations of Drosophila melanogaster.
In order to test the interaction effect of overdominance and random genetic drift on the formation of linkage disequilibria under… 
1976
1976
A contribution to the study of linkage disequilibrium in Drosophila melanogaster.
Linkage disequilibrium was detected in 12 out of 30 cases involivng gene alleles and inversions in three cage populations and in… 
1974
1974
Human migrations and linkage disequilibrium ofHL-A system
A migration with admixture of genes in two populations inducesHL-A linkage disequilibrium or Δ when gene frequencies in the two…