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Limb Deformities, Congenital

Known as: Congenital deformity NOS of unspecified limb, CONGENITAL ABNORMALITY OF LIMB, LIMB MALFORMATION 
Congenital structural deformities of the upper and lower extremities collectively or unspecified.
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (43)

ADULT SYNDROMEAcromegaloid facial appearance syndromeAcromicric DysplasiaAcropectoral syndrome

Broader (2)

Abnormality of limbslimb defects
In BloodUnequal Limb Lengthnursing therapyprevention & control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Retinoid-induced limb malformations.
The developing limb has been studied extensively and is a useful model to study morphogenesis. During embryogenesis, limb… 
Highly Cited
2000
Highly Cited
2000
Stage- and species-specific developmental toxicity of all-trans retinoic acid in four native North American ranids and Xenopus laevis.
Within the last decade, there have been increasing reports of malformed amphibians across North America. Recently, it has been… 
Highly Cited
1998
Highly Cited
1998
The role of p53 and cell death by apoptosis and necrosis in 4-hydroperoxycyclophosphamide-induced limb malformations.
The exposure of embryonic murine limbs in vitro to an activated analog of cyclophosphamide, 4-hydroperoxycyclophosphamide (4OOH… 
Highly Cited
1995
Highly Cited
1995
Mouse embryos lacking RXR alpha are resistant to retinoic-acid-induced limb defects.
Embryonic exposure to the vitamin A metabolite retinoic acid (RA) causes malformations in numerous developing tissues, including… 
Highly Cited
1995
Highly Cited
1995
A second autosomal split hand/split foot locus maps to chromosome 10q24-q25.
Ectrodactyly (split hand/split foot malformation, SHSF) is a human limb malformation characterized by absent central digital rays… 
Highly Cited
1995
Highly Cited
1995
Mapping the mouse dactylaplasia mutation, Dac, and a gene that controls its expression, mdac.
Dactylaplasia is an inherited mouse limb malformation whose manifestation is clearly dependent on the interaction of two genes… 
Highly Cited
1990
Highly Cited
1990
Cyclophosphamide teratogenesis: evidence for compensatory responses to induced cellular toxicity.
Cyclophosphamide (CP) administered ip to pregnant mice on day 10 of gestation (day of plug = day 0) is teratogenic (exencephaly… 
Highly Cited
1981
Highly Cited
1981
Teratogenesis of retinoic acid in rats: susceptible stages and suppression of retinoic acid-induced limb malformations by cycloheximide.
The susceptible stages and the malformation pattern produced by excess retinoic acid were investigated in rat fetuses. Retinoic… 
Highly Cited
1972
Highly Cited
1972
Limb morphogenesis.
Review
1968
Review
1968
Amphibian limb regeneration.
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