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limb defects
Known as:
defect limb
, defects limbs
, limb defect
National Institutes of Health
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Limb Deformities, Congenital
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Thalidomide‐induced limb defects: resolving a 50‐year‐old puzzle
N. Vargesson
Bioessays
2009
Corpus ID: 6341875
Despite the recent discovery that thalidomide causes limb defects by targeting highly angiogenic, immature blood vessels, several…
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Review
2008
Review
2008
Shedding light on an old mystery: Thalidomide suppresses survival pathways to induce limb defects
J. Knobloch
,
U. Rüther
Cell Cycle
2008
Corpus ID: 10690641
Many hypotheses have been proposed to explain the molecular mechanism of thalidomide teratogenicity, in particular regarding to…
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Highly Cited
2004
Highly Cited
2004
Regulation of limb development by the sphingosine 1-phosphate receptor S1p1/EDG-1 occurs via the hypoxia/VEGF axis.
S. Chae
,
J. Paik
,
M. L. Allende
,
R. Proia
,
T. Hla
Developmental Biology
2004
Corpus ID: 19211760
Review
2002
Review
2002
Teratogen-induced limb defects.
L. Holmes
American journal of medical genetics
2002
Corpus ID: 21532452
Limb abnormalities are one of the most common and visible phenotypic effects of several human teratogens. The specific effects…
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Highly Cited
2000
Highly Cited
2000
Maternal occupation in agriculture and risk of limb defects in Washington State, 1980-1993.
L. Engel
,
E. O'Meara
,
S. Schwartz
Scandinavian Journal of Work, Environment and…
2000
Corpus ID: 33039257
OBJECTIVES This study examined the association between maternal occupational exposure to agricultural chemicals and the risk of…
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Highly Cited
1995
Highly Cited
1995
Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring.
G. Shaw
,
C. D. O'Malley
,
C. Wasserman
,
M. Tolarová
,
E. Lammer
American journal of medical genetics
1995
Corpus ID: 32404596
We investigated whether a woman's periconceptional use of a multivitamin containing folic acid was associated with a reduced risk…
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Highly Cited
1987
Highly Cited
1987
Limb body wall complex: I. Pathogenesis.
M. V. Van Allen
,
C. Curry
,
L. Gallagher
American journal of medical genetics
1987
Corpus ID: 23106049
Twenty-five fetuses with limb body wall complex (LBW complex) were evaluated. The diagnosis was based on two out of three of the…
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Highly Cited
1987
Highly Cited
1987
Limb-body wall complex: II. Limb and spine defects.
M. V. Van Allen
,
C. Curry
,
C. Walden
,
L. Gallagher
,
R. Patten
American journal of medical genetics
1987
Corpus ID: 10838891
Limb defects from 25 fetuses with limb-body wall (LBW) complex were evaluated to determine the mechanism of limb damage. The limb…
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Highly Cited
1983
Highly Cited
1983
Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: implications for the study of the fetal alcohol syndrome.
W. Webster
,
D. Walsh
,
S. McEwen
,
A. Lipson
Teratology
1983
Corpus ID: 24708195
To investigate the teratogenic effect of acute alcohol exposure, pregnant C57BL/6J mice were exposed to 25% ethanol (either two…
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Highly Cited
1982
Highly Cited
1982
The classification and development of cadmium-induced limb defects in mice.
K. Messerle
,
W. Webster
Teratology
1982
Corpus ID: 19394901
The aim of this study was to investigate the teratogenic action of cadmium (Cd) on the developing mouse limb. Pregnant mice…
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