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Comparison of the penetration of 14 pesticides through the skin of young and adult rats.
TLDR
In vivo percutaneous absorption of 14 pesticides was studied in young and adult female Fischer 344 rats, at three different dose levels, and the majority of the compounds showed dose-dependent penetration. Expand
Teratogenicity of low doses of all-trans retinoic acid in presomite mouse embryos.
TLDR
The trend toward an increase in the incidence of severe ocular malformations at the lowest dose examined and the fact that subtle ocularmalformations were not taken into account for this study suggest that even lower dosages may be effective. Expand
Cell cycle alterations and cell death in cyclophosphamide teratogenesis.
TLDR
The pattern and magnitude of cell death correlated with cell cycle perturbation and fetal toxicity at term, suggesting a relationship between cell cycleperturbation, cell death, and malformations produced by CP. Expand
A review of the literature on potential reproductive and developmental toxicity of electric and magnetic fields.
TLDR
From a review of the literature, it is concluded that laboratory experimental and epidemiological results to date have not yielded conclusive data to support the contention that such fields induce adverse reproductive effects under the test or environmental conditions studied. Expand
A review on cylindrospermopsin: the global occurrence, detection, toxicity and degradation of a potent cyanotoxin.
TLDR
This review presents an overview of the importance of cylindrospermopsin, its detection, toxicity, worldwide distribution, and lastly, its chemical and biological degradation and removal by natural processes and drinking water treatment processes. Expand
SUPERNUMERARY RIBS IN DEVELOPMENTAL TOXICITY BIOASSAYS AND IN HUMAN POPULATIONS: INCIDENCE AND BIOLOGICAL SIGNIFICANCE
TLDR
The sum of the experimental evidence supports the idea of SNR being composed of two different structures: extra ribs that are permanent dysmorphological structures that may be induced by xenobiotics and/or maternal stress, and ossification sites that mayBe transient variations in the formation of the lateral processes of the vertebrae. Expand
Teratogenic effects of cadmium in rats.
TLDR
The teratogenic effects of subcutaneous injections of cadmium in CD rats were investigated and it was found that the lung/body weight ratios were significantly reduced in fetuses of animals injected with 8 mg/kg CdCl2 on days 14–17 of gestation. Expand
The effect of acute maternal toxicity on fetal development in the mouse.
TLDR
Maternal health status, as measured by the incidence of lethality in the treated groups and by the magnitude of maternal weight gain in surviving females, presents no simple explanation for many manifestations of fetal toxicity, but for seven chemicals including deltamethrin, EBIS, and kepone an increased incidence of supernumerary ribs was observed. Expand
The teratogenic potential of cacodylic acid in the rat and mouse.
TLDR
The results suggest an "apparent no effect level" for this anomaly below 30 mg/kg/day, and incidence of irregular palatine rugae was significantly (p less than 0.001) dose-related. Expand
Further evaluation of an in vivo teratology screen.
TLDR
The assay achieves the requirements for a teratology screening system, but improved predictability would result from the addition of a lower dose level and extension of the dosing period to include later stages of organogenesis. Expand
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