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Leukotriene A4

Known as: LTA4, Leukotriene A-4, Leukotriene A4 [Chemical/Ingredient] 
(2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
4. Biosynthesis of Leukotrienes 5869 4.1. Discovery of the Leukotriene Pathway and a Common Unstable Intermediate 5869 4.2… Expand
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Highly Cited
2009
Highly Cited
2009
[6]-Gingerol, a natural component of ginger, exhibits anti-inflammatory and antitumorigenic activities. Despite its potential… Expand
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Review
2007
Review
2007
Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO… Expand
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Highly Cited
2006
Highly Cited
2006
Variants of the gene ALOX5AP (also known as FLAP) encoding arachidonate 5-lipoxygenase activating protein are known to be… Expand
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Review
2001
Review
2001
  • Z. Kmieć
  • Advances in Anatomy Embryology and Cell Biology
  • 2001
  • Corpus ID: 7714118
The liver lobule is formed by parenchymal cells, i.e., hepatocytes and nonparenchymal cells. In contrast to hepatocytes that… Expand
Review
1994
Review
1994
  • W. Henderson
  • Annals of Internal Medicine
  • 1994
  • Corpus ID: 34810055
Leukotrienes, together with prostaglandins, thromboxanes, and lipoxins, are the major constituents of a group of biologically… Expand
Highly Cited
1990
Highly Cited
1990
Human neutrophils from peripheral blood may physically interact with platelets in several settings including hemostasis… Expand
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Highly Cited
1988
Highly Cited
1988
Transformation of leukotriene (LT) A4 into leukotriene C4 has been found to be carried out by human platelets in a rather… Expand
Review
1987
Review
1987
Arachidonic acid is released from membrane phospholipids upon cell stimulation (for example, by immune complexes and calcium… Expand
Highly Cited
1986
Highly Cited
1986
Leukotriene (LT) synthesis and metabolism were studied in porcine aortic endothelial cells. Leukotrienes were identified by… Expand