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Leukotriene A4

Known as: LTA4, Leukotriene A-4, Leukotriene A4 [Chemical/Ingredient] 
(2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate… 
National Institutes of Health

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15 relations

Narrower (5)

11,12-leukotriene A414,15-dehydroleukotriene A414,15-leukotriene A45,6-methanoleukotriene A4
In BloodProcess of secretionagonistsanalogs & derivatives

Broader (1)

Leukotriene A

Papers overview

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2017
2017
Effect of antileukotriene ( zileuton ) in patients with bronchial asthma ( emphasized reactors , moderate reactors , and non-reactors )
1Department of Pharmacy, Faculty of Medicine,University of Prishtina, Clinical Centre,Prishtina, Kosova. 2Kosovo Occupational… 
2011
2011
[Metabolomics study of anti-platelet effect of Radix Paeoniae Rubra and Radix Paeoniae Alba by UPLC-MS].
OBJECTIVE To study the anti-platelet effect and influence of Radix Paeoniae Rubra and Radix Paeoniae Alba on rat's endogenous… 
2005
2005
Selective inhibition of leukotriene B4 formation by Ebselen: A novel approach to antiinflammatory therapy
Leukotriene B4 (LTB4) is a dihydroxy metabolite of arachidonic acid, released by stimulated leukocytes, and a potent stimulator… 
Review
2003
Review
2003
Leukotriene A 4 Signaling , Inflammation , and Cancer
Chen et al. report in this issue of the Journal that leukotriene A4 hydrolase (LTA4H) was overexpressed in 10 rat esophageal… 
1999
1999
Synthesis of (2S, 5S)- trans-5-(4- fluorophenoxymethyl) -2-(1-N-hydroxy ureidyl-3-butyn-4-yl) -tetrahydrofuran– (CMI-977)
Abstract 
1998
1998
Design of inhibitors of leukotriene biosynthesis and their therapeutic potential
Abstract 
1992
1992
Mechanism-based Inactivation of Leukotriene A4 Hydrolase/ Aminopeptidase by Leukotriene A4
“Suicide” inactivation of leukotriene (LT) A4 hydrolase/aminopeptidase occurs via an irreversible mechanism-based process which… 
Highly Cited
1988
Highly Cited
1988
Characterization of cloned human leukocyte 5-lipoxygenase expressed in mammalian cells.
5-Lipoxygenase has been expressed in a mammalian osteosarcoma cell line transfected with the cloned cDNA for human leukocyte 5… 
1985
1985
Metabolism of leukotrienes by adult and fetal human lungs.
The metabolism of leukotriene (LT) A4, B4, C4, D4, and E4 was studied using both bioassay and reversed phase high performance… 
1982
1982
Formation of leukotrienes C and D and Pharmacologic modulation of their synthesis.
Our attempts to find a physiologically relevant means for inducing leukotriene synthesis in rat peritoneal mononuclear cells have…