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Leukocyte Elastane

Known as: Granulocyte-Derived Elastase, Human Leukocyte Elastase, Elastase, PMN 
An enzyme that catalyzes the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of Ala and Val, with… 
National Institutes of Health

Related topics

Related topics

19 relations
ELANE geneElastase.leukocytary:CCnc:Pt:Plas:QnEnzyme GeneHydrolysis

Broader (2)

ElastasesPancreatic Elastase

Narrower (2)

Medullasinalpha 1-antitrypsin-leukocyte elastase complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1991
Highly Cited
1991
The heterogeneity of human chorionic gonadotropin (hCG). III. The occurrence and biological and immunological activities of nicked hCG.
Nicks, or missing peptide linkages, have been found in hCG beta-subunit between residues 44 and 45 and between residues 47 and 48… 
Highly Cited
1985
Highly Cited
1985
Released granulocytic elastase: an indicator of pathobiochemical alterations in septicemia after abdominal surgery.
To discover the role of lysosomal enzyme release from polymorphonuclear (PMN) leukocytes during septicemia, plasma levels of PMN… 
Highly Cited
1983
Highly Cited
1983
Specific binding by human polymorphonuclear leucocytes of the immunological mediator 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycero-3-phosphorylcholine.
The binding of the platelet-activating factor 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine (AGEPC) by human… 
Highly Cited
1982
Highly Cited
1982
Influenza A virus-induced polymorphonuclear leukocyte dysfunction in the pathogenesis of experimental pneumococcal otitis media
The role of influenza A virus-induced polymorphonuclear leukocyte and eustachian tube dysfunction in the pathogenesis of acute… 
Highly Cited
1981
Highly Cited
1981
Adsorption to fibrin of native fragments of known primary structure from human plasminogen.
Highly Cited
1981
Highly Cited
1981
Stimulation of the elastolytic activity of leukocyte elastase by leukocyte cathepsin G.
Highly Cited
1980
Highly Cited
1980
The degradation of human lung elastin by neutrophil proteinases.
Highly Cited
1977
Highly Cited
1977
The degradation of cartilage proteoglycans by tissue proteinases. Proteoglycan structure and its susceptibility to proteolysis.
1. Proteoglycan was obtained from bovine nasal cartilage by a procedure involving sequential extraction with a low-ionic-strength… 
Highly Cited
1976
Highly Cited
1976
Human lysosomal elastase. Catalytic and immunological properties.
1. The elastase of human spleen was shown to exhibit endopeptidase activity against azo-casein and elastin. 2. Activity against… 
Highly Cited
1970
Highly Cited
1970
Mediators of tissue damage in leukocyte lysosomes. X. Further studies on human granulocyte elastase.
  • A. Janoff
  • Laboratory investigation; a journal of technical…
  • 1970
  • Corpus ID: 21049597
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