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LY 389795
Known as:
LY-389795
, LY389795
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Amino Acids
Bridged Bicyclo Compounds, Heterocyclic
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Synthesis and metabotropic glutamate receptor activity of S-oxidized variants of (-)-4-amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate: identification of potent, selective, and orally…
J. Monn
,
S. M. Massey
,
+11 authors
D. Schoepp
Journal of Medicinal Chemistry
2007
Corpus ID: 29293551
(-)-4-Amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate (LY389795, (-)-3) is a highly potent and selective agonist of…
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Highly Cited
2005
Highly Cited
2005
Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing
C. Jones
,
E. L. Eberle
,
S. Peters
,
J. Monn
,
H. Shannon
Neuropharmacology
2005
Corpus ID: 29424194
Highly Cited
2003
Highly Cited
2003
Comparison of the effect of glutamate receptor modulators in the 6 Hz and maximal electroshock seizure models
M. Barton
,
S. Peters
,
H. Shannon
Epilepsy Research
2003
Corpus ID: 10611625
Highly Cited
2002
Highly Cited
2002
Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats
R. Simmons
,
A. Webster
,
A. Kalra
,
S. Iyengar
Pharmacology, Biochemistry and Behavior
2002
Corpus ID: 33867775
Highly Cited
2001
Highly Cited
2001
Anti-epileptic activity of group II metabotropic glutamate receptor agonists (−)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (−)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6…
R. Moldrich
,
M. Jeffrey
,
A. Talebi
,
P. Beart
,
A. Chapman
,
B. Meldrum
Neuropharmacology
2001
Corpus ID: 26104177
Highly Cited
1999
Highly Cited
1999
Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo[3.1.0] hexane-2,6-dicarboxylic acid (LY354740): identification of two…
J. Monn
,
M. J. Valli
,
+14 authors
D. Schoepp
Journal of Medicinal Chemistry
1999
Corpus ID: 34570124
As part of our ongoing research program aimed at the identification of highly potent, selective, and systemically active agonists…
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Highly Cited
1999
Highly Cited
1999
Neuroprotective Actions of Novel and Potent Ligands of Group I and Group II Metabotropic Glutamate Receptors
A. Kingston
,
M. O'Neill
,
+8 authors
D. Schoepp
Annals of the New York Academy of Sciences
1999
Corpus ID: 267724
ABSTRACT: The role of group I metabotropic glutamate (mGlu) receptors in neurodegeneration is controversial because of the…
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1999
1999
Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795.
A. Kingston
,
M. O'Neill
,
A. Lam
,
K. Bales
,
J. Monn
,
D. Schoepp
European Journal of Pharmacology
1999
Corpus ID: 4520819
In rat cortical neuronal cultures, metabotropic glutamate (mGlu) receptor agonists: LY354740 (+)-2-aminobicyclo[3.1.0]hexane-2…
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