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National Institutes of Health
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Identification and partial characterization of two steroid 5α‐reductase isozymes in the canine prostate
Corpus ID: 28437653
The dog has been extensively used as an in vivo model to test the pharmacokinetics and effects on pathological prostatic growth…
Pharmacological and molecular evidence for the expression of the two steroid 5α‐reductase isozymes in normal and hyperplastic human prostatic cells in culture
Corpus ID: 19849292
Whereas the embryological development of the human prostate is clearly dependent on steroid 5α‐reductase (5α‐R) type 2 expression…
Characterization of type I 5 alpha-reductase activity in DU145 human prostatic adenocarcinoma cells.
The Journal of steroid biochemistry and molecular…
Corpus ID: 20300893
The conversion of testosterone (T) to dihydrotestosterone (DHT) has been demonstrated to be catalysed by at least two isoforms of…
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