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LY 300164

Known as: LY-300164, LY300164 
National Institutes of Health

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2 relations

Broader (2)

GYKI 53405Talampanel

Papers overview

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2006
2006
Talampanel improves the functional deficit after transient focal cerebral ischemia in rats. A 30-day follow up study
Highly Cited
2003
Highly Cited
2003
Talampanel, a New Antiepileptic Drug: Single‐ and Multiple‐dose Pharmacokinetics and Initial 1‐Week Experience in Patients with Chronic Intractable Epilepsy
Summary:  Purpose: Talampanel (LY300164), a potent and selective α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionate (AMPA)‐receptor… 
2003
2003
Pharmacological heterogeneity of release-regulating presynaptic AMPA/kainate receptors in the rat brain: study with receptor antagonists
2002
2002
Influence of several convulsants on the protective activity of a non-competitive AMPA/kainate antagonist, LY 300164, and lamotrigine against maximal electroshock in mice.
Aminophylline (50-100 mg/kg) and strychnine (0.125-0.5 mg/kg) significantly raised the ED50 values of LY 300164 against maximal… 
2001
2001
Glutamate receptor antagonists differentially affect the protective activity of conventional antiepileptics against amygdala-kindled seizures in rats
2001
2001
AMPA and GABA(B) receptor antagonists and their interaction in rats with a genetic form of absence epilepsy.
2000
2000
The AMPA/kainate receptor antagonist, LY 300164, increases the anticonvulsant effects of diazepam
Abstract. The aim of this study was to evaluate the influence of 7-acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo(4… 
1999
1999
Stereoselective neuroprotection by novel 2,3-benzodiazepine non-competitive AMPA antagonists against non-NMDA receptor-mediated excitotoxicity in primary rat hippocampal cultures
1998
1998
Effects of AMPA receptor antagonists on dopamine-mediated behaviors in mice
Abstract Current data indicate that dopaminergic and glutamatergic neurotransmitter systems interact. The role of α-amino-3… 
1998
1998
LY 300164, a novel antagonist of AMPA/kainate receptors, potentiates the anticonvulsive activity of antiepileptic drugs.
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