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Talampanel

Known as: (R)-(-)-1-(4-Aminophenyl)-3-acetyl-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine, 1-(4'-aminophenyl)-3-acetyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine, 7-acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo(4,5-h)benzodiazepine 
A synthetic derivative of dioxolo-benzodiazepine with anti-seizure activity. Talampanel antagonizes the AMPA (alpha-amino-3-hydroxy-5-methyl-4… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Abstract Our objective was to determine if chronic treatment with the non-competitive AMPA antagonist talampanel is efficacious… 
Highly Cited
2010
Highly Cited
2010
Purpose: Novel agents are currently combined with radiation and temozolomide (RT + TMZ) in newly diagnosed glioblastoma using… 
Highly Cited
2009
Highly Cited
2009
PURPOSE Recent data suggest that the glutamatergic system is important in the proliferation and migration of glioblastoma… 
Review
2006
Highly Cited
2002
Highly Cited
2002
Abstract—The authors report a double-blind, placebo-controlled, crossover study of talampanel in 49 patients with refractory…