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LY 235959

Known as: LY-235959, LY235959 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Antiparkinson AgentsExcitatory Amino Acid AntagonistsIsoquinolines

Papers overview

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Highly Cited
2008
Highly Cited
2008
NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats
RationaleN-Methyl-d-aspartate (NMDA) receptors have an important role in different forms of behavioral and neural plasticity… 
2008
2008
Increased efficacy of μ-opioid agonist-induced antinociception by metabotropic glutamate receptor antagonists in C57BL/6 mice: comparison with (−)-6-phosphonomethyl-deca-hydroisoquinoline-3…
RationaleRecent experimental data suggest that metabotropic glutamate receptor (mGluR) antagonists with selectivity for mGluR1… 
2007
2007
Lipopolysaccharide- and glutamate-induced hypothalamic hydroxyl radical elevation and fever can be suppressed by N-methyl-D-aspartate-receptor antagonists.
The purpose of the current study was to explore the effects of N-methyl-D-aspartate (NMDA)-receptor antagonists (MK-801 and… 
2007
2007
Cardiovascular effects of l-glutamate microinjection in the supraoptic nucleus of unanaesthetized rats
2007
2007
Continuous exposure to the competitive N-methyl-d-aspartate receptor antagonist, LY235959, facilitates escalation of cocaine consumption in Sprague–Dawley rats
RationaleChronic high dose consumption of cocaine is associated with significant negative effects to individual users and society… 
2005
2005
Effects of the Competitive N-Methyl-d-aspartate Receptor Antagonist, LY235959 [(-)-6-Phosphonomethyl-deca-hydroisoquinoline-3-carboxylic Acid], on Responding for Cocaine under Both Fixed and…
It is difficult to determine the precise role of the N-methyl-d-aspartate (NMDA) receptor system in the reinforcing effects of… 
Highly Cited
2004
Highly Cited
2004
Modulation of morphine analgesia by site-specific N-methyl-d-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time
2003
2003
Effects of NMDA receptor antagonists on acute μ-opioid analgesia in the rat
2002
2002
Attenuation of Acute Morphine Withdrawal in the Neonatal Rat by the Competitive NMDA Receptor Antagonist LY235959
2001
2001
Glutamate receptor antagonists differentially affect the protective activity of conventional antiepileptics against amygdala-kindled seizures in rats
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