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LTB4R gene

Known as: P2Y7, PURINERGIC RECEPTOR P2Y, G PROTEIN-COUPLED, 7, BLT1 
This gene is in involved in G protein-coupled receptor signal transduction and chemotaxis.
National Institutes of Health

Related topics

Related topics

12 relations
CCRL1 protein, humanCMKLR1 geneCMKLR1 protein, humanCardiac Muscle Contraction

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LTB4R wt Allele

Papers overview

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Highly Cited
2018
Highly Cited
2018
Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1.
Most G-protein-coupled receptors (GPCRs) are stabilized in common in the inactive state by the formation of the sodium ion… 
Highly Cited
2005
Highly Cited
2005
Inhibition of Atherogenesis in BLT1-Deficient Mice Reveals a Role for LTB4 and BLT1 in Smooth Muscle Cell Recruitment
Background—It is known that 5-lipoxygenase and its product, leukotriene B4 (LTB4), are highly expressed in several human… 
Highly Cited
2003
Highly Cited
2003
Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment
Leukotriene B4 (LTB4) was originally described as a potent lipid myeloid cell chemoattractant, rapidly generated from innate… 
Highly Cited
2003
Highly Cited
2003
Structure-based analysis of GPCR function: conformational adaptation of both agonist and receptor upon leukotriene B4 binding to recombinant BLT1.
Highly Cited
2000
Highly Cited
2000
A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders.
Leukotriene B(4) (LTB(4)) is a potent chemoattractant and activator of both granulocytes and macrophages. The actions of LTB(4… 
Highly Cited
2000
Highly Cited
2000
Targeted Disruption of the Leukotriene B4Receptor in Mice Reveals Its Role in Inflammation and Platelet-Activating Factor–Induced Anaphylaxis
Leukotrienes are derived from arachidonic acid and serve as mediators of inflammation and immediate hypersensitivity. Leukotriene… 
Highly Cited
2000
Highly Cited
2000
Cloning and characterization of cDNA encoding a novel human leukotriene B(4) receptor.
By homology screening using BLAST searches of expressed sequence tags (ESTs), we have found a previously unidentified cDNA… 
Highly Cited
2000
Highly Cited
2000
Cell-Specific Transcriptional Regulation of Human Leukotriene B4 Receptor Gene
Leukotriene B4 (LTB4) is a lipid mediator that activates leukocytes and is involved in host defense and inflammation. BLT1, a… 
Highly Cited
1998
Highly Cited
1998
Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits.
COS-7 cells transfected with the leukotriene (LT) B4 receptor (BLTR) cDNA were unable to produce LTB4-induced inositol phosphates… 
Highly Cited
1996
Highly Cited
1996
Cloning of cDNA encoding a putative chemoattractant receptor.
Based on polymerase chain reaction (PCR) utilizing degenerate primers directed to the second and sixth transmembrane domains of… 
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