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LTB4R wt Allele

Known as: P2Y7, BLT1, BLTR 
Human LTB4R wild-type allele is located within 14q11.2-q12 and is approximately 4 kb in length. This allele, which encodes leukotriene B4 receptor 1… 
National Institutes of Health

Related topics

Related topics

9 relations
14q11.2-q12Cardiac Muscle ContractionG Protein-Coupled Receptor SignalingHomo sapiens

Broader (1)

LTB4R gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Resolvin E1 Selectively Interacts with Leukotriene B4 Receptor BLT1 and ChemR23 to Regulate Inflammation1
Resolvin E1 (RvE1) is a potent anti-inflammatory and proresolving mediator derived from omega-3 eicosapentaenoic acid generated… 
Review
2003
Review
2003
BLT1 and BLT2: the leukotriene B(4) receptors.
Highly Cited
2003
Highly Cited
2003
Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment
Leukotriene B4 (LTB4) was originally described as a potent lipid myeloid cell chemoattractant, rapidly generated from innate… 
Highly Cited
2003
Highly Cited
2003
Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues
Leukotriene B4 (LTB4) is a potent chemoattractant for myeloid leukocytes, which express BLT1, the high-affinity receptor for LTB4… 
Highly Cited
2003
Highly Cited
2003
Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein.
Highly Cited
2002
Highly Cited
2002
Leukotriene B4 Receptor Antagonism Reduces Monocytic Foam Cells in Mice
Leukotriene B4 (LTB4) is a potent chemotactic agent that activates monocytes through the LTB4 receptor (BLTR). We tested the… 
Highly Cited
2000
Highly Cited
2000
A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders.
Leukotriene B(4) (LTB(4)) is a potent chemoattractant and activator of both granulocytes and macrophages. The actions of LTB(4… 
Highly Cited
2000
Highly Cited
2000
Targeted Disruption of the Leukotriene B4Receptor in Mice Reveals Its Role in Inflammation and Platelet-Activating Factor–Induced Anaphylaxis
Leukotrienes are derived from arachidonic acid and serve as mediators of inflammation and immediate hypersensitivity. Leukotriene… 
Highly Cited
2000
Highly Cited
2000
Bltr Mediates Leukotriene B4–Induced Chemotaxis and Adhesion and Plays a Dominant Role in Eosinophil Accumulation in a Murine Model of Peritonitis
Leukotriene B4 (LTB4) is a potent chemoattractant active on multiple leukocytes, including neutrophils, macrophages, and… 
Highly Cited
1999
Highly Cited
1999
Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.
Polymorphonuclear neutrophil (PMN) activation is pivotal in acute inflammation and injury from reperfusion. To elucidate… 
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