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LIPOPROTEIN LIPASE
Known as:
Lipemia-Clearing Factor
, Heparin Clearing Factor
, Lipoprotein Lipase [Chemical/Ingredient]
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An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme…
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National Institutes of Health
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Related topics
Related topics
22 relations
Broader (2)
Carboxylic Ester Hydrolases
carboxylesterase
Enzyme Gene
Esterase Gene
Hydrolase
Hydrolysis
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Narrower (2)
Lipase deficiency combined
lipolytic enzyme L2, Aspergillus oryzae
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Lipoprotein lipase: from gene to obesity.
Hong Wang
,
R. Eckel
American journal of physiology. Endocrinology and…
2009
Corpus ID: 6762620
Lipoprotein lipase (LPL) is a multifunctional enzyme produced by many tissues, including adipose tissue, cardiac and skeletal…
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Highly Cited
2003
Highly Cited
2003
Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials.
R. Mensink
,
P. Zock
,
A. Kester
,
M. Katan
The American journal of clinical nutrition
2003
Corpus ID: 3672783
BACKGROUND The effects of dietary fats on the risk of coronary artery disease (CAD) have traditionally been estimated from their…
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Review
2002
Review
2002
Lipoprotein lipase: structure, function, regulation, and role in disease
J. R. Mead
,
S. Irvine
,
D. Ramji
Journal of Molecular Medicine
2002
Corpus ID: 40089672
Abstract. Lipoprotein lipase (LPL) catalyses the hydrolysis of the triacylglycerol component of circulating chylomicrons and very…
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Highly Cited
2001
Highly Cited
2001
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
Jason K. Kim
,
J. J. Fillmore
,
+9 authors
G. Shulman
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 26013192
Insulin resistance in skeletal muscle and liver may play a primary role in the development of type 2 diabetes mellitus, and the…
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Review
1998
Review
1998
Mechanism of action of fibrates on lipid and lipoprotein metabolism.
B. Staels
,
J. Dallongeville
,
J. Auwerx
,
K. Schoonjans
,
E. Leitersdorf
,
J. Fruchart
Circulation
1998
Corpus ID: 5858864
Treatment with fibrates, a widely used class of lipid-modifying agents, results in a substantial decrease in plasma triglycerides…
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Highly Cited
1996
Highly Cited
1996
PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.
K. Schoonjans
,
J. Peinado-Onsurbe
,
+5 authors
J. Auwerx
The EMBO journal
1996
Corpus ID: 21106372
Increased activity of lipoprotein lipase (LPL) may explain the hypotriglyceridemic effects of fibrates, thiazolidinediones and…
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Review
1996
Review
1996
Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis.
I. Goldberg
Journal of lipid research
1996
Corpus ID: 15065078
Although it has been known for over 50 years that lipoprotein lipase (LPL) hydrolyzes triglyceride in chylomicrons, during the…
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Highly Cited
1995
Highly Cited
1995
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.
P. Kern
,
M. Saghizadeh
,
J. Ong
,
R. Bosch
,
R. Deem
,
R. Simsolo
The Journal of clinical investigation
1995
Corpus ID: 29135139
A previous study reported the increased expression of the cytokine TNF in the adipose tissue of genetically obese rodents. To…
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Highly Cited
1991
Highly Cited
1991
Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein.
U. Beisiegel
,
W. Weber
,
G. Bengtsson-Olivecrona
Proceedings of the National Academy of Sciences…
1991
Corpus ID: 23037936
Chylomicron catabolism is known to be initiated by the enzyme lipoprotein lipase (triacylglycero-protein acylhydrolase, EC 3.1.1…
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Review
1989
Review
1989
Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases.
R. Eckel
The New England journal of medicine
1989
Corpus ID: 11493288
Lipoprotein lipase is an important regulator of lipid and lipoprotein metabolism. It also contributes to the lipid and energy…
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