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LIPOPROTEIN LIPASE

Known as: Lipemia-Clearing Factor, Heparin Clearing Factor, Lipoprotein Lipase [Chemical/Ingredient] 
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme… 
National Institutes of Health

Related topics

Related topics

22 relations

Broader (2)

Carboxylic Ester Hydrolasescarboxylesterase
Enzyme GeneEsterase GeneHydrolaseHydrolysis
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Narrower (2)

Lipase deficiency combinedlipolytic enzyme L2, Aspergillus oryzae

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Lipoprotein lipase: from gene to obesity.
  • Hong Wang, R. Eckel
  • American journal of physiology. Endocrinology and…
  • 2009
  • Corpus ID: 6762620
Lipoprotein lipase (LPL) is a multifunctional enzyme produced by many tissues, including adipose tissue, cardiac and skeletal… 
Highly Cited
2003
Highly Cited
2003
Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials.
BACKGROUND The effects of dietary fats on the risk of coronary artery disease (CAD) have traditionally been estimated from their… 
Review
2002
Review
2002
Lipoprotein lipase: structure, function, regulation, and role in disease
Abstract. Lipoprotein lipase (LPL) catalyses the hydrolysis of the triacylglycerol component of circulating chylomicrons and very… 
Highly Cited
2001
Highly Cited
2001
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
Insulin resistance in skeletal muscle and liver may play a primary role in the development of type 2 diabetes mellitus, and the… 
Review
1998
Review
1998
Mechanism of action of fibrates on lipid and lipoprotein metabolism.
Treatment with fibrates, a widely used class of lipid-modifying agents, results in a substantial decrease in plasma triglycerides… 
Highly Cited
1996
Highly Cited
1996
PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.
Increased activity of lipoprotein lipase (LPL) may explain the hypotriglyceridemic effects of fibrates, thiazolidinediones and… 
Review
1996
Review
1996
Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis.
  • I. Goldberg
  • Journal of lipid research
  • 1996
  • Corpus ID: 15065078
Although it has been known for over 50 years that lipoprotein lipase (LPL) hydrolyzes triglyceride in chylomicrons, during the… 
Highly Cited
1995
Highly Cited
1995
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.
A previous study reported the increased expression of the cytokine TNF in the adipose tissue of genetically obese rodents. To… 
Highly Cited
1991
Highly Cited
1991
Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein.
Chylomicron catabolism is known to be initiated by the enzyme lipoprotein lipase (triacylglycero-protein acylhydrolase, EC 3.1.1… 
Review
1989
Review
1989
Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases.
  • R. Eckel
  • The New England journal of medicine
  • 1989
  • Corpus ID: 11493288
Lipoprotein lipase is an important regulator of lipid and lipoprotein metabolism. It also contributes to the lipid and energy… 
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