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Abiraterone acetate is a prodrug of abiraterone, a selective inhibitor of CYP17, the enzyme catalyst for two essential… Expand Prasugrel and clopidogrel inhibit platelet aggregation through active metabolite formation. Prasugrel's active metabolite (R… Expand PURPOSE
Antiandrogen withdrawal (AAWD) results in a prostate-specific antigen (PSA) response (decline in PSA level of > or =50… Expand Abstract The chemotherapy currently available for leishmaniasis is far from satisfactory. Resistance to the pentavalent… Expand The glass forming properties of ketoconazole were investigated using differential scanning calorimetry (DSC), by quench cooling… Expand Interaction between ketoconazole, itraconazole, and midazolam was investigated in a double‐blind, randomized crossover study of… Expand OBJECTIVE
To examine prospectively the effects of ketoconazole on the pharmacokinetics and electrocardiographic repolarization… Expand Ketoconazole has recently been shown to interfere with steroidogenesis in patients and rat in vitro systems. In this study we… Expand Ketoconazole, a new oral drug used to treat systemic and superficial mycoses, inhibits sterol synthesis in fungi. The development… Expand Ketoconazole, a broad-spectrum, antifungal drug that is administered orally, has been shown to inhibit sterol synthesis in fungi… Expand