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Ketoconazole

Known as: Ketoconazolum, Ketoconazol, Piperazine, 1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-, cis- 
A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
PURPOSE Abiraterone acetate is a prodrug of abiraterone, a selective inhibitor of CYP17, the enzyme catalyst for two essential… Expand
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Highly Cited
2010
Highly Cited
2010
To the Editor: Cushing's disease, which is caused by an adrenocorticotropin-secreting pituitary adenoma, is associated with… Expand
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Highly Cited
2007
Highly Cited
2007
Prasugrel and clopidogrel inhibit platelet aggregation through active metabolite formation. Prasugrel's active metabolite (R… Expand
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Highly Cited
2004
Highly Cited
2004
PURPOSE Antiandrogen withdrawal (AAWD) results in a prostate-specific antigen (PSA) response (decline in PSA level of > or =50… Expand
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Review
2003
Review
2003
Abstract The chemotherapy currently available for leishmaniasis is far from satisfactory. Resistance to the pentavalent… Expand
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Review
2003
Review
2003
UNLABELLED Extensive clinical use has confirmed that tacrolimus (Prograf) is a key option for immunosuppression after… Expand
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Highly Cited
2001
Highly Cited
2001
The glass forming properties of ketoconazole were investigated using differential scanning calorimetry (DSC), by quench cooling… Expand
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Highly Cited
1994
Highly Cited
1994
Interaction between ketoconazole, itraconazole, and midazolam was investigated in a double-blind, randomized crossover study of… Expand
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Highly Cited
1983
Highly Cited
1983
Ketoconazole has recently been shown to interfere with steroidogenesis in patients and rat in vitro systems. In this study we… Expand
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Highly Cited
1982
Highly Cited
1982
Ketoconazole, a new oral drug used to treat systemic and superficial mycoses, inhibits sterol synthesis in fungi. The development… Expand
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