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Ketoconazole

Known as: Ketoconazolum, Ketoconazol, Piperazine, 1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-, cis- 
A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a… 
National Institutes of Health

Related topics

Related topics

42 relations
24 HR Nevirapine 400 MG Extended Release Oral TabletAntifungal AgentsAstemizoleAzoles

Broader (2)

Cytochrome P-450 CYP3A InhibitorsImidazoles

Narrower (7)

ExtinaKetodermKetozoleMal-A-Ket

Papers overview

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1988
1988
An extractive colorimetric method for the determination of ketoconazole from pharmaceutical preparations.
An extractive colorimetric method for the determination of ketoconazole from pharmaceutical preparations is described. The method… 
1986
1986
An investigation into the effects of ketoconazole on testicular function in Wistar rats.
Ketoconazole was administered orally to sexually mature Wistar rats and testicular function assessed. A single oral dose of 24 mg… 
1986
1986
Ketoconazole's Inhibition of Fungal Antigen‐Induced Thymidine Uptake by Lymphocytes from Patients with Psoriasis
Ketoconazole, an oral antifungal imidazole, has been effective in some refractory cases of psoriasis, particularly those with… 
1986
1986
Effects of ketoconazole on rat ovarian steroidogenic enzymatic activities.
Ketoconazole (K) is an antifungal imidazole derivative which is a potent inhibitor of steroid biosynthesis in rodents and humans… 
1984
1984
Ketoconazole concentrations in human skin blister fluid and plasma.
To investigate ketoconazole penetration into skin, a single oral dose of 200 mg was administered to six healthy subjects. Plasma… 
1984
1984
Arachidonic acid metabolites mediate early burn edema.
Standard burns were sequentially produced on the backs of Sprague-Dawley rats at 0, 1, 2, and 2 1/2 hr, followed by the IV… 
1983
1983
Ketoconazole treatment of Candida esophagitis--a prospective study of 12 cases.
Candida infection of the esophagus is a frequent occurrence in both symptomatic and asymptomatic patients. In the present study… 
1983
1983
Control of systemic spread of Candida albicans with ketoconazole in the stomachs of mice treated with cytarabine.
Attempts were made to colonize the gastrointestinal tract of outbred CD-1 mice with Candida albicans or Candida tropicalis before… 
1982
1982
Hepatic dysfunction and ketoconazole therapy.
Excerpt To the editor: A previous communication from our institution described a case of biopsy-proven toxic hepatitis in a… 
1981
1981
Chromohyphomycosis: Treatment With Ketoconazole
Chromomycoses (CM) are a group of chronic, indolent ^ fungal infections of man and animals, in which the cutaneous and…