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Ketoconazole

Known as: Ketoconazolum, Ketoconazol, Piperazine, 1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-, cis- 
A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
PURPOSE Abiraterone acetate is a prodrug of abiraterone, a selective inhibitor of CYP17, the enzyme catalyst for two essential… 
Highly Cited
2004
Highly Cited
2004
PURPOSE Antiandrogen withdrawal (AAWD) results in a prostate-specific antigen (PSA) response (decline in PSA level of > or =50… 
Highly Cited
1999
Highly Cited
1999
Antiandrogenic chemicals alter sexual differentiation by a variety of mechanisms, and as a consequence, they induce different… 
Highly Cited
1993
Highly Cited
1993
OBJECTIVE To examine prospectively the effects of ketoconazole on the pharmacokinetics and electrocardiographic repolarization… 
Highly Cited
1983
Highly Cited
1983
Ketoconazole has recently been shown to interfere with steroidogenesis in patients and rat in vitro systems. In this study we… 
Highly Cited
1982
Highly Cited
1982
Ketoconazole, a new oral drug used to treat systemic and superficial mycoses, inhibits sterol synthesis in fungi. The development… 
Highly Cited
1982
Highly Cited
1982
Ketoconazole, a broad-spectrum, antifungal drug that is administered orally, has been shown to inhibit sterol synthesis in fungi…