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Ketoconazole

Known as: Ketoconazolum, Ketoconazol, Piperazine, 1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-, cis- 
A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a… 
National Institutes of Health

Related topics

Related topics

42 relations
24 HR Nevirapine 400 MG Extended Release Oral TabletAntifungal AgentsAstemizoleAzoles

Broader (2)

Cytochrome P-450 CYP3A InhibitorsImidazoles

Narrower (7)

ExtinaKetodermKetozoleMal-A-Ket

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Characterization of hot-melt extruded drug delivery systems for onychomycosis.
Highly Cited
2003
Highly Cited
2003
Hydrosoluble formazan XTT: its application to natural products drug discovery for Leishmania.
Highly Cited
2000
Highly Cited
2000
In Vitro Activities of Ketoconazole, Econazole, Miconazole, and Melaleuca alternifolia (Tea Tree) Oil against Malassezia Species
ABSTRACT The in vitro activities of ketoconazole, econazole, miconazole, and tea tree oil against 54 Malassezia isolates were… 
Highly Cited
1999
Highly Cited
1999
Liarozole Acts Synergistically with 1α,25-Dihydroxyvitamin D3 to Inhibit Growth of DU 145 Human Prostate Cancer Cells by Blocking 24-Hydroxylase Activity.
1α,25-Dihydroxyvitamin D3[ 1,25-(OH)2D3] inhibits the proliferation of many cancer cells in culture, but not the aggressive human… 
Highly Cited
1999
Highly Cited
1999
Prophylactic antibiotics in patients undergoing laser resurfacing of the skin.
Highly Cited
1998
Highly Cited
1998
Involvement of human cytochromes P450 (CYP) in the reductive metabolism of AQ4N, a hypoxia activated anthraquinone di-N-oxide prodrug.
Highly Cited
1986
Highly Cited
1986
Retinol metabolism in LLC-PK1 Cells. Characterization of retinoic acid synthesis by an established mammalian cell line.
Highly Cited
1986
Highly Cited
1986
Isolation of a cytochrome P-450 structural gene from Saccharomyces cerevisiae.
Highly Cited
1985
Highly Cited
1985
Reversible adrenal insufficiency induced by ketoconazole.
KETOCONAZOLE, an imidazole antifungal drug, blocks testicular and adrenal steroid synthesis in a dosedependent and time-dependent… 
Review
1984
Review
1984
Symposium on infectious complications of neoplastic disease (Part II). Chemoprophylaxis of fungal infections.
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