Antimicrobial activity of essential oils and other plant extracts
The results of this study support the notion that plant essential oils and extracts may have a role as pharmaceuticals and preservatives.
Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties
This review summarizes recent developments in understanding of the antimicrobial and anti-inflammatory activities of the tea tree oil and its components, as well as clinical efficacy.
Mechanism of Action of Melaleuca alternifolia (Tea Tree) Oil on Staphylococcus aureus Determined by Time-Kill, Lysis, Leakage, and Salt Tolerance Assays and Electron Microscopy
The predisposition to lysis, the loss of 260-nm-absorbing material, the lost of tolerance to NaCl, and the altered morphology seen by electron microscopy all suggest that tea tree oil and its components compromise the cytoplasmic membrane.
Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia.
The antimicrobial activity of eight components of tea tree oil was evaluated using disc diffusion and broth microdilution methods and reasonable agreement between minimum inhibitory concentrations and zones of inhibition was found.
Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil
The objective is to investigate the in vitro antifungal activity of the components of Melaleuca alternifolia (tea tree) oil to find out if it acts as a ‘spatially aggregating agent’ or ‘neutralizer’ to fungi.
Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes
- P. Hart, C. Brand, C. Carson, T. Riley, R. Prager, J. Finlay-Jones
- Biology, MedicineInflammation Research
- 1 November 2000
The water-soluble components of tea tree oil can suppress pro-inflammatory mediator production by activated human monocytes and reduce the production in vitro of tumour necrosis factor-α, IL-1β and IL-10 by lipopolysaccharide-activated human peripheral blood monocytes.
Susceptibility of methicillin-resistant Staphylococcus aureus to the essential oil of Melaleuca alternifolia.
- C. Carson, B. Cookson, H. Farrelly, T. Riley
- Biology, MedicineJournal of Antimicrobial Chemotherapy
- 1 March 1995
All 66 isolates of Staphylococcus aureus tested were susceptible to the essential oil of Melaleuca alternifolia, or tea tree oil, in disc diffusion and modified broth microdilution methods, suggestingTea tree oil may be useful in the treatment of MRSA carriage.
A review of the toxicity of Melaleuca alternifolia (tea tree) oil.
Broth micro-dilution method for determining the susceptibility of Escherichia coli and Staphylococcus aureus to the essential oil of Melaleuca alternifolia (tea tree oil).
A broth micro-dilution method was used to examine the susceptibility of Escherichia coli and Staphylococcus aureus to the essential oil of Melaleuca alternifolia (tea tree oil) to enhance the solubility of tea tree oil in the test medium.
In-vitro activity of essential oils, in particular Melaleuca alternifolia (tea tree) oil and tea tree oil products, against Candida spp.
Tests on three intra-vaginalTea tree oil products showed these products to have MICs and minimum fungicidal concentrations comparable to those of non-formulated tea tree oil, indicating that the tea treeOil contained in these products has retained its anticandidal activity.