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Antimicrobial activity of essential oils and other plant extracts
TLDR
The results of this study support the notion that plant essential oils and extracts may have a role as pharmaceuticals and preservatives. Expand
Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties
TLDR
This review summarizes recent developments in understanding of the antimicrobial and anti-inflammatory activities of the tea tree oil and its components, as well as clinical efficacy. Expand
Mechanism of Action of Melaleuca alternifolia (Tea Tree) Oil on Staphylococcus aureus Determined by Time-Kill, Lysis, Leakage, and Salt Tolerance Assays and Electron Microscopy
TLDR
The predisposition to lysis, the loss of 260-nm-absorbing material, the lost of tolerance to NaCl, and the altered morphology seen by electron microscopy all suggest that tea tree oil and its components compromise the cytoplasmic membrane. Expand
Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia.
TLDR
The antimicrobial activity of eight components of tea tree oil was evaluated using disc diffusion and broth microdilution methods and reasonable agreement between minimum inhibitory concentrations and zones of inhibition was found. Expand
Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil
TLDR
The objective is to investigate the in vitro antifungal activity of the components of Melaleuca alternifolia (tea tree) oil to find out if it acts as a ‘spatially aggregating agent’ or ‘neutralizer’ to fungi. Expand
Susceptibility of methicillin-resistant Staphylococcus aureus to the essential oil of Melaleuca alternifolia.
TLDR
All 66 isolates of Staphylococcus aureus tested were susceptible to the essential oil of Melaleuca alternifolia, or tea tree oil, in disc diffusion and modified broth microdilution methods, suggestingTea tree oil may be useful in the treatment of MRSA carriage. Expand
Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes
TLDR
The water-soluble components of tea tree oil can suppress pro-inflammatory mediator production by activated human monocytes and reduce the production in vitro of tumour necrosis factor-α, IL-1β and IL-10 by lipopolysaccharide-activated human peripheral blood monocytes. Expand
Broth micro-dilution method for determining the susceptibility of Escherichia coli and Staphylococcus aureus to the essential oil of Melaleuca alternifolia (tea tree oil).
TLDR
A broth micro-dilution method was used to examine the susceptibility of Escherichia coli and Staphylococcus aureus to the essential oil of Melaleuca alternifolia (tea tree oil) to enhance the solubility of tea tree oil in the test medium. Expand
A review of the toxicity of Melaleuca alternifolia (tea tree) oil.
TLDR
Data from individual components suggest that TTO has the potential to be developmentally toxic if ingested at higher doses, however, TTO and its components are not genotoxic. Expand
Antifungal effects of Melaleuca alternifolia (tea tree) oil and its components on Candida albicans, Candida glabrata and Saccharomyces cerevisiae.
TLDR
Data from this study support the hypothesis that tea tree oil and components exert their antifungal actions by altering membrane properties and compromising membrane-associated functions. Expand
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