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JUP gene

Known as: JUP, PLAKOGLOBIN, DP3 
This gene is involved in cellular adhesion and modulates cadherin interactions.
National Institutes of Health

Related topics

Related topics

7 relations
Cell AdhesionJUP protein, humanLigand BindingSignal Transduction

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JUP wt Allele

Papers overview

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2008
2008
Thermal effects of circumplanetary disc formation around proto‐gas giant planets
The formation of a circumplanetary disc and accretion of angular momentum on to a protoplanetary system are investigated using… 
Highly Cited
2000
Highly Cited
2000
Development of cationic liposome formulations for intratracheal gene therapy of early lung cancer
Regional (intratracheal or aerosol) delivery of cationic liposome-DNA complexes for gene therapy of lung disease offers distinct… 
Highly Cited
1999
Highly Cited
1999
Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice.
Plakoglobin, a protein belonging to the Armadillo-repeat gene family, is the only component that adherens junctions and… 
Highly Cited
1999
Highly Cited
1999
Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling.
In Wnt signaling, beta-catenin and plakoglobin transduce signals to the nucleus through interactions with TCF-type transcription… 
Highly Cited
1998
Highly Cited
1998
Coexpression of both types of desmosomal cadherin and plakoglobin confers strong intercellular adhesion.
Desmosomes are unique intercellular junctions in that they invariably contain two types of transmembrane cadherin molecule… 
Highly Cited
1998
Highly Cited
1998
Reduced expression of plakoglobin indicates an unfavorable prognosis in subsets of patients with non-small-cell lung cancer.
PURPOSE Plakoglobin is thought to play a key role in cadherin-mediated epithelial cell adhesion, because it is a common component… 
1995
1995
Plakoglobin: kinetics of synthesis, phosphorylation, stability, and interactions with desmoglein and E-cadherin.
We have analyzed the kinetics of synthesis, phosphorylation, and stability of the soluble and insoluble plakoglobin (PG) and… 
Review
1994
Review
1994
Unraveling the cytoplasmic interactions of the cadherin superfamily.
Cadherins are a rapidly growing family of calcium-dependent morphoregulatory proteins. Members of three subsets of this family… 
Highly Cited
1994
Highly Cited
1994
Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation.
Plakoglobin is a cytoplasmic protein localized in both adherens junctions and desmosomes. Little is known about its function, but… 
Highly Cited
1992
Highly Cited
1992
Plakoglobin and β-catenin : distinct but closely related : authors' reply
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