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JUP protein, human

Known as: JUP, Desmoplakin-3, Plakoglobin 
Junction plakoglobin (744 aa, ~82 kDa) is encoded by the human JUP gene. This protein is involved in adherens junction assembly.
National Institutes of Health

Related topics

Related topics

12 relations
Cell AdhesionClusters of differentiationDesmosomeHomo sapiens

Broader (2)

desmoplakinplakoglobin

Papers overview

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2010
2010
Novel missense mutations in exon 15 of desmoglein-2: Role of the intracellular cadherin segment in arrhythmogenic right ventricular cardiomyopathy?
2008
2008
Identification of a novel intermediate filament-linked N-cadherin/gamma-catenin complex involved in the establishment of the cytoarchitecture of differentiated lens fiber cells.
2004
2004
β-Catenin and Plakoglobin N- and C-tails Determine Ligand Specificity*
β-Catenin and plakoglobin are related proteins involved in the regulation of adherens junctions and desmosomes. Moreover, by… 
2000
2000
Expression of a single pair of desmosomal glycoproteins renders the corneal epithelium unique amongst stratified epithelia.
PURPOSE To determine desmosomal glycoprotein isoform expression in bovine corneal, limbal, and conjunctival epithelium and… 
2000
2000
The amino- and carboxyl-terminal tails of (beta)-catenin reduce its affinity for desmoglein 2.
beta-catenin and plakoglobin are members of the armadillo family of proteins and were first identified as components of… 
Highly Cited
1999
Highly Cited
1999
Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice.
Plakoglobin, a protein belonging to the Armadillo-repeat gene family, is the only component that adherens junctions and… 
Highly Cited
1998
Highly Cited
1998
Reduced expression of plakoglobin indicates an unfavorable prognosis in subsets of patients with non-small-cell lung cancer.
PURPOSE Plakoglobin is thought to play a key role in cadherin-mediated epithelial cell adhesion, because it is a common component… 
1995
1995
Plakoglobin: kinetics of synthesis, phosphorylation, stability, and interactions with desmoglein and E-cadherin.
We have analyzed the kinetics of synthesis, phosphorylation, and stability of the soluble and insoluble plakoglobin (PG) and… 
Highly Cited
1994
Highly Cited
1994
Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells.
Because the cell adhesion molecule epithelial cadherin (E-cadherin) is absent in many invasive carcinomas, we transfected the E… 
Highly Cited
1987
Highly Cited
1987
Immunolocalization of plakoglobin in endothelial junctions: identification as a special type of Zonulae adhaerentes
We have characterized the junctions between endothelial cells of diverse blood vessels at the light and electron microscopic… 
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