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Isoquinoline Alkaloid Biosynthesis Pathway

Known as: isoquinoline alkaloid formation, isoquinoline alkaloid biosynthetic process, isoquinoline alkaloid synthesis 
The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Total synthesis of the Kopsia lapidilecta alkaloid (+/-)-lapidilectine B.
The total synthesis of Kopsia lapidilecta alkaloid (+/-)-lapidilectine B is described. Notable elements of this synthesis include… 
Highly Cited
2003
Highly Cited
2003
Biomimetic approach to communesin B (a.k.a. nomofungin)
Highly Cited
1999
Highly Cited
1999
Synthesis and cytotoxic activities of a new benzo[c]phenanthridine alkaloid, 7-hydroxynitidine, and some 9-oxygenated benzo[c]phenanthridine derivatives.
[formula: see text] A new benzo[c]phenanthridine alkaloid, 7-hydroxynitidine, was synthesized by a novel synthetic procedure. The… 
Highly Cited
1997
Highly Cited
1997
Mechanism of alkaloid cyclopeptide synthesis in the ergot fungus Claviceps purpurea.
Highly Cited
1996
Highly Cited
1996
Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies
Highly Cited
1993
Highly Cited
1993
Calystegins, a novel class of alkaloid glycosidase inhibitors.
The alkaloid extract from roots of naturally growing Convolvulus arvensis, purified by ion-exchange chromatography, showed… 
Highly Cited
1991
Highly Cited
1991
Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.
Water-soluble analogues of the antitumor alkaloid camptothecin (1) were prepared in which aminoalkyl groups were introduced into… 
Highly Cited
1983
Highly Cited
1983
Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridine (fagaronine), with nucleic acids.
Highly Cited
1982
Highly Cited
1982
HL 725, an extremely potent inhibitor of platelet phosphodiesterase and induced platelet aggregation in vitro.
Highly Cited
1974
Highly Cited
1974
Allenic and acetylenic spiropiperidine alkaloids from the neotropical frog, Dendrobates histrionicus.
Four analogs of the acetylenic alkaloid, histrionicotoxin (C19H25NO) and the allenic alkaloid, isodihydrohistrionicotoxin have… 
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