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Isoquinoline Alkaloid Biosynthesis Pathway

Known as: isoquinoline alkaloid formation, isoquinoline alkaloid biosynthetic process, isoquinoline alkaloid synthesis 
The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
P2X7 receptor antagonists: a patent review (2010–2015)
  • J. Park, Y. Kim
  • Expert opinion on therapeutic patents
  • 2017
    • Corpus ID: 23442805
ABSTRACT Introduction: The P2X7 receptor (P2X7R) is a unique subtype among the family of seven purinergic P2X receptors, which… Expand
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Review
2017
Review
2017
Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance
ABSTRACT Schistosomiasis, a major neglected tropical disease, affects more than 250 million people worldwide. Treatment of… Expand
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Highly Cited
2013
Highly Cited
2013
Rh(III)-catalyzed synthesis of multisubstituted isoquinoline and pyridine N-oxides from oximes and diazo compounds.
Multisubstituted isoquinoline and pyridine N-oxides have been prepared by Rh(III)-catalyzed cyclization of oximes and diazo… Expand
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Highly Cited
2008
Highly Cited
2008
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
CONTEXT Berberine, a natural plant alkaloid, is usually used as an antibiotic drug. The potential glucose-lowering effect of… Expand
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Highly Cited
2008
Highly Cited
2008
An efficient low-temperature route to polycyclic isoquinoline salt synthesis via C-H activation with [Cp*MCl2]2 (M = Rh, Ir).
Bi-, tri-, and tetracyclic isoquinoline salts were readily synthesized in excellent yields at room temperature from readily… Expand
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Highly Cited
2005
Highly Cited
2005
Urea- and thiourea-substituted cinchona alkaloid derivatives as highly efficient bifunctional organocatalysts for the asymmetric addition of malonate to nitroalkenes: inversion of configuration at C9…
 
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Highly Cited
2002
Highly Cited
2002
Evolutionary Origins and Ecological Consequences of Endophyte Symbiosis with Grasses
Over the past 20 yr much has been learned about a unique symbiotic interaction between fungal endophytes and grasses. The fungi… Expand
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Review
2002
Review
2002
Visualising microglial activation in vivo
In health, microglia reside as quiescent guardian cells ubiquitously, but isolated without any cell‐cell contacts amongst… Expand
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Highly Cited
1990
Highly Cited
1990
Chelerythrine is a potent and specific inhibitor of protein kinase C.
The benzophenanthridine alkaloid chelerythrine is a potent, selective antagonist of the Ca++/phospholopid-dependent protein… Expand
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Highly Cited
1980
Highly Cited
1980
Inhibition of lysosomal alpha-mannosidase by swainsonine, an indolizidine alkaloid isolated from Swainsona canescens.
An indolizidine alkaloid (swainsonine) was isolated from the plant Swainsona canescens. Swainsonine is a specific and potent… Expand
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