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  • Influence
Pyrrolizidine alkaloid plants, metabolism and toxicity.
More than 350 PAs have been identified in over 6,000 plants in the Boraginaceae, Compositae, and Leguminosae families (Table 1). About half of the identified PAs are toxic and several have been shownExpand
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Current Research on Reducing Pre‐ and Post‐harvest Aflatoxin Contamination of U.S. Almond, Pistachio, and Walnut
Aflatoxins are considered to be potent carcinogens and teratogens to humans and farm animals. A variety of species of the fungal genus Aspergillus (mainly A. flavus and A. parasiticus) synthesizeExpand
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Elucidation of the functional genomics of antioxidant-based inhibition of aflatoxin biosynthesis.
  • J. Kim, J. Yu, +7 authors B. Campbell
  • Biology, Medicine
  • International journal of food microbiology
  • 29 February 2008
Caffeic acid (3,4-dihydroxycinnamic acid, 12 mM) added to a fat-based growth medium reduces >95% of aflatoxin production by Aspergillus flavus NRRL 3357, without affecting fungal growth. MicroarrayExpand
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Honey from plants containing pyrrolizidine alkaloids: a potential threat to health.
Following scientific risk assessments, several countries have imposed strict regulations on herbal medicines containing 1,2-dehydro-pyrrolizidine alkaloids. Using published data on the plants used inExpand
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Inhibitory effects of naturally occurring compounds on aflatoxin B(1) biotransformation.
Effects of naturally occurring compounds from plants on biotransformation of a mycotoxin, aflatoxin B(1), were evaluated. Among 77 naturally occurring compounds tested, anthraquinones, coumarins, andExpand
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  • PDF
Polyhydroxylated alkaloids -- natural occurrence and therapeutic applications.
Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. These alkaloids can be potent and highly selective glycosidase inhibitors and are arousing greatExpand
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Pyrrolizidine alkaloids in food: a spectrum of potential health consequences
Contamination of grain with 1,2-dehydropyrrolizidine ester alkaloids (dehydroPAs) and their N-oxides is responsible for large incidents of acute and subacute food poisoning, with high morbidity andExpand
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Alkaloidal components in the poisonous plant, Ipomoea carnea (Convolvulaceae).
Natural intoxication of livestock by the ingestion of Ipomoea carnea (Convolvulaceae) sometimes occurs in tropical regions of the world. Polyhydroxylated alkaloids were isolated from the leaves,Expand
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Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease.
Large outbreaks of acute food-related poisoning, characterized by hepatic sinusoidal obstruction syndrome, hemorrhagic necrosis, and rapid liver failure, occur on a regular basis in some countries.Expand
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