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New insights on trehalose: a multifunctional molecule.
Trehalose is a nonreducing disaccharide in which the two glucose units are linked in an alpha,alpha-1,1-glycosidic linkage. This sugar is present in a wide variety of organisms, including bacteria,Expand
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Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains.
  • A. Elbein
  • Chemistry, Medicine
  • Annual review of biochemistry
  • 1987
A number of glycoproteins have oligosaccharides linked to protein in a GlcNAc----asparagine bond. These oligosaccharides may be either of the complex, the high-mannose or the hybrid structure. EachExpand
  • 903
  • 18
Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.
Kifunensine, produced by the actinomycete Kitasatosporia kifunense 9482, is an alkaloid that corresponds to a cyclic oxamide derivative of 1-amino mannojirimycin. This compound was reported to be aExpand
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Inhibitors of the biosynthesis and processing of N-linked oligosaccharides.
  • A. Elbein
  • Medicine
  • CRC critical reviews in biochemistry
  • 1984
A number of glycoproteins have oligosaccharides linked to protein in a GlcNAc----asparagine bond. These oligosaccharides may be either of the complex, the high-mannose or the hybrid structure. EachExpand
  • 127
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Trehalose synthase of Mycobacterium smegmatis: purification, cloning, expression, and properties of the enzyme.
Trehalose synthase (TreS) catalyzes the reversible interconversion of trehalose (glucosyl-alpha,alpha-1,1-glucose) and maltose (glucosyl-alpha1-4-glucose). TreS was purified from the cytosol ofExpand
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Last Step in the Conversion of Trehalose to Glycogen
We show that Mycobacterium smegmatis has an enzyme catalyzing transfer of maltose from [14C]maltose 1-phosphate to glycogen. This enzyme was purified 90-fold from crude extracts and characterized.Expand
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A novel trehalase from Mycobacterium smegmatis − purification, properties, requirements
Trehalose is a nonreducing disaccharide of glucose (α,α‐1,1‐glucosyl‐glucose) that is essential for growth and survival of mycobacteria. These organisms have three different biosynthetic pathways toExpand
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Purification, Cloning, Expression, and Properties of Mycobacterial Trehalose-phosphate Phosphatase*
The trehalose-phosphate phosphatase (TPP) was purified from the cytosol of Mycobacterium smegmatis to near homogeneity using a variety of conventional steps to achieve a purification of aboutExpand
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Purification to homogeneity and properties of plant glucosidase I.
  • Y. Zeng, A. Elbein
  • Biology, Medicine
  • Archives of biochemistry and biophysics
  • 1 July 1998
Glucosidase I was purified about 3600-fold to apparent homogeneity from the microsomal fraction of mung bean seedlings. The purified enzyme removed the terminal alpha1,2-linked glucose fromExpand
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