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Isocitrate Dehydrogenase (NAD+)

Known as: Dehydrogenase, NAD Isocitrate, Isocitrate:NAD+ oxidoreductase (decarboxylating), Isocitrate Dehydrogenase [Chemical/Ingredient] 
An enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It… 
National Institutes of Health

Related topics

Related topics

17 relations

Narrower (5)

AceK protein, E coliICDH protein, ArabidopsisIDH2, humanisocitrate dehydrogenase (NADP+)

Broader (2)

Alcohol Oxidoreductasesrespiratory enzyme
Citric Acid CycleIDH3A geneIn BloodProcess of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas
Diffuse gliomas are up till now graded based upon morphology. Recent findings indicate that isocitrate dehydrogenase (IDH… 
Highly Cited
2012
Highly Cited
2012
Detection of 2-Hydroxyglutarate in IDH-Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy
2-Hydroxyglutarate, a metabolite overproduced in IDH-mutated gliomas, can be detected noninvasively in patients with brain tumors… 
Review
2002
Review
2002
Enzyme redundancy and the importance of 2-oxoglutarate in plant ammonium assimilation.
Ammonium is the reduced nitrogen form available to plants for assimilation into amino acids. This is achieved by the GS/GOGAT… 
Highly Cited
1998
Highly Cited
1998
Cadmium toxicity effects on growth, mineral and chlorophyll contents, and activities of stress related enzymes in young maize plants (Zea mays L.)
Plants were cultivated in a nutrient solution containing increasing cadmium concentrations (i.e. 0.001–25 µM), under strictly… 
Highly Cited
1994
Highly Cited
1994
Nitric oxide as a potential pathological mechanism in demyelination: Its differential effects on primary glial cellsin vitro
Review
1992
Review
1992
Carbon catabolite repression in yeast.
Control of gene expression is a basic regulatory mechanism of living organisms. In microorganisms, glucose or other rapidly… 
Highly Cited
1991
Highly Cited
1991
Proteins released from Mycobacterium tuberculosis during growth
Proteins secreted from Mycobacterium tuberculosis during growth are believed to be important for protective immunity against… 
Highly Cited
1976
Highly Cited
1976
Activities of citrate synthase and NAD+-linked and NADP+-linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates.
1. The activities of citrate synthase, NAD+-linked and NADP+-linked isocitrate dehydrogenase were measured in muscles from a… 
Highly Cited
1972
Highly Cited
1972
Salt responses of enzymes from species differing in salt tolerance.
Enzymes which are affected by the addition of inorganic salts during in vitro assay were extracted from salt-sensitive Phaseolus… 
Highly Cited
1964
Highly Cited
1964
The oxidation of citrate, isocitrate and cis-aconitate by isolated mitochondria.
There are five oxidative steps involved in the conversion of pyruvate into carbon dioxide and water in the tricarboxylic acid… 
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