Iodocyanopindolol

Known as: I-Cyanopindolol, 1H-Indole-2-carbonitrile, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-3-iodo-, I Cyanopindolol 
A highly selective and specific beta antagonist that is used to characterize beta-adrenoceptors.
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
alpha2-Adrenergic receptors (ARs) play a key role in regulating neurotransmitter release in the central and peripheral… (More)
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1996
1996
Evidence from ventricular preparations of cat, sheep, rat and dog suggests that both β1-adrenoceptors (β1AR) and β2-adrenoceptors… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Aging decreases cardiac beta-adrenergic responsiveness in model systems and in humans in vivo. The purpose of this… (More)
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1991
1991
Binding studies with (-)-[125I]cyanopindolol (ICYP) were conducted to characterize beta-adrenoceptors in plantaris and soleus… (More)
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1990
1990
The cardiac beta-adrenoceptor adaptation to physical activity was investigated in rats which were subjected to a six-week… (More)
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1988
1988
Beta-adrenergic receptors were characterized in human fat cell membranes using 125I-labeled cyanopindolol (125I-labeled CYP) and… (More)
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1988
1988
In this study, [125I]iodocyanopindolol ([125I]ICYP), in the presence of isoproterenol, was used to label 5-hydroxytryptamine1B (5… (More)
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1986
1986
Using the radioligand beta-adrenergic blocker [125I]cyanopindolol (ICYP), we have characterized the beta-adrenergic receptors on… (More)
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Highly Cited
1986
Highly Cited
1986
We developed methods for identifying beta-adrenergic receptors in human right ventricular endomyocardial biopsy tissue with the… (More)
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Highly Cited
1985
Highly Cited
1985
The pharmacological characteristics of the binding of [3H]8-OH-DPAT ([3H]8-hydroxy-2(di-n-propylamino)tetralin, [125I]CYP… (More)
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