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Iodocyanopindolol

Known as: I-Cyanopindolol, 1H-Indole-2-carbonitrile, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-3-iodo-, I Cyanopindolol 
A highly selective and specific beta antagonist that is used to characterize beta-adrenoceptors.
National Institutes of Health

Related topics

Related topics

8 relations

Broader (1)

Adrenergic beta-Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
2004
Highly Cited
2004
(±)[125Iodo]cyanopindolol, a new ligand for β-adrenoceptors: Identification and quantitation of subclasses of β-adrenoceptors in guinea pig
Summary(±)[125Iodo]cyanopindolol (ICYP) is a radioligand which binds with an extraordinarily high affinity and specificity to… 
Highly Cited
1995
Highly Cited
1995
Role of beta-adrenergic receptor downregulation in the peak exercise response in patients with heart failure due to idiopathic dilated cardiomyopathy.
Highly Cited
1992
Highly Cited
1992
The positive chronotropic effect induced by BRL 37344 and CGP 12177, two beta-3 adrenergic agonists, does not involve cardiac beta adrenoceptors but baroreflex mechanisms.
The presence of a beta-3 adrenoceptor (in addition to the classical beta-1 and beta-2 adrenoceptors) and its involvement in the… 
Highly Cited
1990
Highly Cited
1990
Decrease in rat cardiac beta 1- and beta 2-adrenoceptors by training and endurance exercise.
Highly Cited
1988
Highly Cited
1988
Application of [125I]iodocyanopindolol to measure 5-hydroxytryptamine1B receptors in the brain of the rat.
In this study, [125I]iodocyanopindolol ([125I]ICYP), in the presence of isoproterenol, was used to label 5-hydroxytryptamine1B (5… 
Highly Cited
1988
Highly Cited
1988
The catecholamine binding site of the beta-adrenergic receptor is formed by juxtaposed membrane-spanning domains.
Highly Cited
1986
Highly Cited
1986
Beta-adrenergic receptors on human suppressor, helper, and cytolytic lymphocytes.
Highly Cited
1985
Highly Cited
1985
β-Adrenoceptor blocking agents recognize a subpopulation of serotonin receptors in brain
Highly Cited
1985
Highly Cited
1985
β-Adrenoceptor subtypes in the human brain: autoradiographic localization
Highly Cited
1983
Highly Cited
1983
Delipidation of a beta-adrenergic receptor preparation and reconstitution by specific lipids.
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