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Iodocyanopindolol

Known as: I-Cyanopindolol, 1H-Indole-2-carbonitrile, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-3-iodo-, I Cyanopindolol 
A highly selective and specific beta antagonist that is used to characterize beta-adrenoceptors.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Functional studies have demonstrated that adrenoceptor agonist-evoked relaxation is mediated primarily by β3-adrenergic receptors… Expand
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Highly Cited
2004
Highly Cited
2004
Summary(±)[125Iodo]cyanopindolol (ICYP) is a radioligand which binds with an extraordinarily high affinity and specificity to… Expand
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Highly Cited
2004
Highly Cited
2004
Summary[125Iodo]cyanopindolol [(±)-ICYP], a potent and selective ligand for β-adrenoceptors, exhibited complex biphasic… Expand
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Highly Cited
1994
Highly Cited
1994
BackgroundAging decreases cardiac β–adrenergic responsiveness in model systems and in humans in vivo. The purpose of this study… Expand
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Highly Cited
1988
Highly Cited
1988
In this study, [125I]iodocyanopindolol ([125I]ICYP), in the presence of isoproterenol, was used to label 5-hydroxytryptamine1B (5… Expand
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Highly Cited
1987
Highly Cited
1987
The functional significance of conserved polar amino acids within the putative transmembrane region of the beta-adrenergic… Expand
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Highly Cited
1986
Highly Cited
1986
We developed methods for identifying beta-adrenergic receptors in human right ventricular endomyocardial biopsy tissue with the… Expand
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Highly Cited
1986
Highly Cited
1986
Using the radioligand beta-adrenergic blocker [125I]cyanopindolol (ICYP), we have characterized the beta-adrenergic receptors on… Expand
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Highly Cited
1985
Highly Cited
1985
The pharmacological characteristics of the binding of [3H]8-OH-DPAT ([3H]8-hydroxy-2(di-n-propylamino)tetralin, [125I]CYP… Expand
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Highly Cited
1985
Highly Cited
1985
The interaction of beta-adrenoceptor blocking agents with serotonin receptors in rat brain was analyzed by quantitative light… Expand
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