Skip to search formSkip to main contentSkip to account menu

Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs

A new class of drugs that selectively block serotonin M-receptors on peripheral neurones are described, some of which are the most potent of any pharmacological class yet reported.
View on Springer (opens in a new tab)

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

View on Elsevier (opens in a new tab)

(±)[125Iodo]cyanopindolol, a new ligand for β-adrenoceptors: Identification and quantitation of subclasses of β-adrenoceptors in guinea pig

The low dissociation constant of ICYP in combination with its high specific radioactivity allows binding studies to be carried out with small protein and ligand concentrations, e.g. 3 μg protein per assay in guinea pig lung membranes.
View on Springer (opens in a new tab)

The pharmacology and function of 5-HT3receptors

View on Elsevier (opens in a new tab)

Strain-Specific Synthesis of Mycophenolic Acid by Penicillium roqueforti in Blue-Veined Cheese

Twenty of 80 strains of Penicillium roqueforti were able to produce up to 600 mg of mycophenolic acid (MPA) liter in 2% yeast extract-5% sucrose broth and Toxicity of MPA was tested with two established human cell lines and one established pig kidney cell line.
View on ASMUSA (opens in a new tab)

β-Adrenoceptor blocking agents recognize a subpopulation of serotonin receptors in brain

View on Elsevier (opens in a new tab)

Study of the contractile effect of 5-hydroxytryptamine (5-HT) in the isolated longitudinal muscle strip from guinea-pig ileum

It is concluded that in longitudinal muscle strips from the ileum of adult guinea-pigs a contractile action of 5-HT can be mediated by the activation of three independent receptors.
View on Springer (opens in a new tab)

Subclasses of beta-adrenoceptors--a quantitative estimation of beta 1- and beta 2- adrenoceptors in guinea pig and human lung.

  • G. Engel
  • Biology, Medicine
    Postgraduate medical journal
  • 1981
Analysis of data from displacement curves by means of a curve fitting procedure and non-linear regression analysis indicated that in both tissues beta 1- and beta 2-type adrenoceptors coexisted, suggesting that the 'cardioselectivity ratio" of a compound is the same in the guinea pig and in man.
View on PubMed (opens in a new tab)

5-HT1 receptor agonists attenuate the naloxone-induced jumping behaviour in morphine-dependent mice.

View on PubMed (opens in a new tab)

5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus

Data support the concept that 5-HT stimulated adenylate cyclase activity in rat hippocampus is mediated by a5-HT1A receptor, as pharmacologically characterised with a series of agonists and antagonists of various structural classes.
View on Springer (opens in a new tab)
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)