Skip to search formSkip to main contentSkip to account menu

Interleukin 6 Receptor

Known as: IL-6 Receptors, Receptor, IL6, IL 6 Receptor 
Cell surface receptors that are specific for INTERLEUKIN-6. They are present on T-LYMPHOCYTES, mitogen-activated B-LYMPHOCYTES, and peripheral… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (2)

CD AntigensInterleukin Receptor
IL6R geneIn Bloodagonistsantagonists & inhibitors

Narrower (2)

IL6R protein, humaninterleukin-6 receptor alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Medical Management of Rheumatoid Arthritis
SIR,-The second report of the Royal College of Physicians-Smoking and Health Now'-once more gives clear evidence of the… 
Highly Cited
1999
Highly Cited
1999
Interleukin-6 directly modulates stem cell factor-dependent development of human mast cells derived from CD34(+) cord blood cells.
In the present study, we attempted to clarify the effects of interleukin-6 (IL-6) on the growth and properties of human mast… 
Highly Cited
1998
Highly Cited
1998
Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation.
The functional receptor for the inflammatory cytokine IL-6 is composed of the ligand binding IL-6 receptor alpha chain (IL-6R… 
Highly Cited
1998
Highly Cited
1998
Combination of Interleukin‐6 and Soluble Interleukin‐6 Receptors Induces Differentiation and Activation of JAK‐STAT and MAP Kinase Pathways in MG‐63 Human Osteoblastic Cells
Studies on the role of interleukin‐6 (IL‐6) in bone metabolism have been accumulating. However, its effects on osteoblasts are… 
Highly Cited
1998
Highly Cited
1998
Human myeloma cells shed the interleukin‐6 receptor: inhibition by tissue inhibitor of metalloproteinase‐3 and a hydroxamate‐based metalloproteinase inhibitor
Interleukin‐6 (IL‐6) is the major growth factor for human myeloma cells, exerting its effect through the IL‐6 receptor (IL‐6R). A… 
Highly Cited
1996
Highly Cited
1996
IL-6-inducible complexes on an IL-6 response element of the junB promoter contain Stat3 and 36 kDa CRE-like site binding protein(s).
The junB gene is one of immediate-early genes whose expression are regulated by a variety of extracellular stimuli and play… 
Review
1992
Review
1992
IL-6 receptor and mechanism of signal transduction.
Highly Cited
1991
Highly Cited
1991
IL-6 and IL-6 receptor modulation by IFN-gamma and tumor necrosis factor-alpha in human monocytic cell line (THP-1). Priming effect of IFN-gamma.
The present work is a detailed study of the mechanism of IFN-gamma- and TNF-alpha-triggered IL-6 secretion and IL-6 gene… 
Highly Cited
1991
Highly Cited
1991
Preparation of soluble murine IL-6 receptor and anti-murine IL-6 receptor antibodies.
Starting with a previously isolated cDNA clone encoding murine IL-6R, a stable transformed Chinese hamster ovary cell line… 
Highly Cited
1990
Highly Cited
1990
Functional murine interleukin 6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesis
Two species of the cDNAs encoding murine IL-6-R (one is abnormal and the other authentic) have been cloned from a plasmacytoma… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)