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IL6R protein, human
Known as:
interleukin 6 receptor protein, human
, gp80
, CD126 Antigen
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Interleukin-6 receptor subunit alpha (468 aa, ~52 kDa) is encoded by the human IL6R gene. This protein plays a role in regulation of the immune…
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National Institutes of Health
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Related topics
Related topics
22 relations
Biologic Development
Cell Proliferation
Cytokine Receptor Gene
Cytokine Signaling Process
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Broader (2)
Interleukin 6 Receptor
Interleukin-6 Receptor alpha Subunit
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.
C. Garbers
,
N. Monhasery
,
+6 authors
J. Scheller
Biochimica et Biophysica Acta
2014
Corpus ID: 10652895
Highly Cited
2003
Highly Cited
2003
Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma
T. Hideshima
,
D. Chauhan
,
+7 authors
K. Anderson
Oncogene
2003
Corpus ID: 26488808
Proteasome inhibitor PS-341 is one of the most promising novel agents against multiple myeloma (MM). We have previously shown…
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Highly Cited
2003
Highly Cited
2003
The Exocyst Affects Protein Synthesis by Acting on the Translocation Machinery of the Endoplasmic Reticulum*
J. Lipschutz
,
V. Lingappa
,
K. Mostov
Journal of Biological Chemistry
2003
Corpus ID: 12049445
We previously showed that the exocyst complex specifically affected the synthesis and delivery of secretory and basolateral…
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Highly Cited
2002
Highly Cited
2002
Reduced oviposition of Boophilus microplus feeding on sheep vaccinated with vitellin.
R. Tellam
,
D. Kemp
,
+5 authors
P. Willadsen
Veterinary parasitology
2002
Corpus ID: 25429591
Review
1997
Review
1997
The structural and functional basis of cytokine receptor activation: lessons from the common beta subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5…
C. Bagley
,
J. Woodcock
,
F. Stomski
,
A. Lopez
Blood
1997
Corpus ID: 26181911
CYTOKINE RECEPTORS are cell-surface glycoproteins that bind specifically to cytokines and transduce their signals. These…
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Highly Cited
1997
Highly Cited
1997
Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.
S. C. Lin
,
T. Yamate
,
+6 authors
S. Manolagas
Journal of Clinical Investigation
1997
Corpus ID: 36511443
Both estrogen and androgen exert their antiosteoporotic effects, at least in part, by inhibiting IL-6 production, thereby…
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Highly Cited
1996
Highly Cited
1996
Interleukin‐6 Induces Expression of Peripherin and Cooperates with Trk Receptor Signaling to Promote Neuronal Differentiation in PC12 Cells
E. Sterneck
,
D. Kaplan
,
Peter F Johnson
Journal of Neurochemistry
1996
Corpus ID: 10985313
Abstract: In contrast to the intensively studied nerve growth factor (NGF)‐related family of cytokines, relatively little is…
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Highly Cited
1993
Highly Cited
1993
The soluble interleukin‐6 receptor is generated by shedding
J. Mülberg
,
H. Schooltink
,
+6 authors
S. Rose-John
European Journal of Immunology
1993
Corpus ID: 22834660
The ligand‐binding subunit (gp80) of the human interleukin‐6 receptor (IL‐6R) was transiently expressed in COS‐7 cells. The…
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Highly Cited
1992
Highly Cited
1992
The hepatic interleukin‐6 receptor Down‐regulation of the interleukin‐6 binding subunit (gp80) by its ligand
D. Zohlnhöfer
,
L. Graeve
,
S. Rose-John
,
H. Schooltink
,
E. Dittrich
,
P. Heinrich
FEBS Letters
1992
Corpus ID: 22549621
Highly Cited
1983
Highly Cited
1983
Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue
C. Damsky
,
J. Richa
,
D. Solter
,
K. Knudsen
,
C. Buck
Cell
1983
Corpus ID: 11633953
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