IL6R protein, human

Known as: interleukin 6 receptor protein, human, gp80, CD126 Antigen 
Interleukin-6 receptor subunit alpha (468 aa, ~52 kDa) is encoded by the human IL6R gene. This protein plays a role in regulation of the immune… (More)
National Institutes of Health

Related topics

Related topics

22 relations
Biologic DevelopmentCell ProliferationCytokine Receptor GeneCytokine Signaling Process
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Broader (2)

Interleukin 6 ReceptorInterleukin-6 Receptor alpha Subunit

Papers overview

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Highly Cited
2009
Highly Cited
2009
Interleukin-6 and neural stem cells: more than gliogenesis.
Besides its wide range of action as a proinflammatory cytokine in the immune system, interleukin-6 (IL-6) has also attracted much… (More)
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2004
2004
IL-6 as an intracrine growth factor for renal carcinoma cell lines.
Interleukin-6 (IL-6) is produced at high levels by renal cell carcinoma cell lines. The molecular mechanisms involved in its… (More)
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Highly Cited
2003
Highly Cited
2003
Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma
Proteasome inhibitor PS-341 is one of the most promising novel agents against multiple myeloma (MM). We have previously shown… (More)
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2003
2003
The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum.
We previously showed that the exocyst complex specifically affected the synthesis and delivery of secretory and basolateral… (More)
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2002
2002
Cerebrospinal fluid and serum protein levels of tumour necrosis factor-alpha (TNF-alpha) interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R gp80) in multiple sclerosis patients.
The aim of this study was to evaluate soluble proteins of tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and IL-6… (More)
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1997
1997
Inflammatory mediators in children with protein-energy malnutrition.
Edema is a typical sign in kwashiorkor, which is present in a subset of patients with protein-energy-malnutrition (PEM). The… (More)
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1996
1996
Interleukin-6 induces expression of peripherin and cooperates with Trk receptor signaling to promote neuronal differentiation in PC12 cells.
In contrast to the intensively studied nerve growth factor (NGF)-related family of cytokines, relatively little is known about… (More)
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1994
1994
Gp80 (clusterin; TRPM-2) mRNA level is enhanced in human renal clear cell carcinomas
The gp80 glycoprotein complex (clusterin, apolipoprotein J, TRPM-2) is a widely expressed protein that has been attributed… (More)
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Highly Cited
1993
Highly Cited
1993
The soluble interleukin-6 receptor is generated by shedding.
The ligand-binding subunit (gp80) of the human interleukin-6 receptor (IL-6R) was transiently expressed in COS-7 cells. The… (More)
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1989
1989
Identification of an octapeptide involved in homophilic interaction of the cell adhesion molecule gp80 of dictyostelium discoideum
During development of Dictyostelium discoideum, a surface glycoprotein of Mr 80,000 (gp80) is known to mediate EDTA-resistant… (More)
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