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IL6R gene
Known as:
INTERLEUKIN 6 RECEPTOR
, CD126
, INTERLEUKIN 6 RECEPTOR, ALPHA
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This gene in involved in the regulation of cellular responses; such as the immune response, hematopoiesis, and acute-phase inflammatory reactions.
National Institutes of Health
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Related topics
Related topics
8 relations
Cytokine Signaling Process
IL6R protein, human
IL6R wt Allele
Intercellular Communication Process
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Association Between IL6R Polymorphisms and Cachexia Phenotype in Patients with Pancreatic Ductal Adenocarcinoma
Nicholas Polster
,
Joseph E. Rupert
,
A. Young
,
T. Zimmers
Proceedings of IMPRS
2019
Corpus ID: 213657628
Background: Cachexia, manifested as progressive adipose and muscle wasting, affects up to 80% of patients with pancreatic ductal…
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2018
2018
Abstract 050: Phenome Wide Association Study of IL6R Variants Identifies a Drug Target for Cardiovascular Disease and Inflammation
Tianxi Cai
,
Yichi Zhang
,
+17 authors
K. Liao
2018
Corpus ID: 86417800
Background: Individuals with an interleukin 6 receptor (IL6R) genetic variant not on IL6R blocking therapy have biomarker…
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2014
2014
Identification of cis-regulatory variations in the IL6R gene through the inheritance assessment of allelic transcription.
Soo A. Oh
,
Hyejin Byun
,
E. Jang
,
Sangkyun Jeong
Biochimica et Biophysica Acta
2014
Corpus ID: 25088694
BACKGROUND The level of circulating interleukin-6 receptor in human blood varies depending on the genetic and/or physiological…
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2014
2014
Изучение ассоциации однонуклеотидного полиморфизма rs4129267 гена рецептора интерлейкина-6 (IL6R) с риском развития бронхиальной астмы
Разводовская Анастасия Владимировна
,
Черкашина Ирина Ивановна
,
Никулина Светлана Юрьевна
,
Шестовицкий Владимир Андреевич
,
Воевода Михаил Иванович
,
Максимов Владимир Николаевич
2014
Corpus ID: 85858649
Study of the influence of polymorphism rs 4129267 of IL6R gene on the susceptibility to the development of bronchial asthma among…
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2013
2013
A genomic and transcriptomic approach to the high bone mass phenotype: evidences of heterogeneity and of additive effects of TWIST1, IL6R, DLX3, and PPARG
P. Sarrión
,
L. Mellibovsky
,
+12 authors
S. Balcells
2013
Corpus ID: 83539181
Prevalence of HBM in the BARCOS cohort = 0.6% RESULTS A genomic and transcriptomic approach to the high bone mass phenotype…
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2013
2013
IL6 trans-signaling promotes functional recovery of hypofunctional phagocytes through STAT3 activation during peritonitis
Tsuyoshi Onogawa
,
T. Saito‐Taki
,
Hiroshi Yamamoto
,
T. Wada
Inflammation Research
2013
Corpus ID: 253589020
The role of high interleukin 6 (IL6) levels has not been clearly explained in severe sepsis. We show that the augmentation of the…
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2013
2013
proinflammatory trans-signaling function of neutrophils Apoptosis is a natural stimulus of IL6R shedding and contributes to the
A. Jones
,
S. Rose‐John
,
+6 authors
C. Fielding
2013
Corpus ID: 89445406
2013
2013
Functional analysis of the p . Asp 358 Ala ( rs 2228145 ) variant
S. Harrison
,
Andrew J. P. Smith
,
+24 authors
S. Humphries
2013
Corpus ID: 7873095
Seamus C. Harrison 1,2*, Andrew J.P. Smith1, Gregory T. Jones3, Daniel I. Swerdlow4, Riaz Rampuri1, Matthew J. Bown5, on behalf…
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2009
2009
Association Studies of the IL6R D358A with Type 2 Diabetes in Han Chinese Population of Hubei
Li-L. Shi
2009
Corpus ID: 75229127
Objective:To investigate the association of D358A polymorphism in exon 9 of interleukin 6 receptor gene(IL6R)and the…
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1996
1996
Clinical significance of elevated soluble interleukin 6 receptor levels in patients with plasma cell disorders.
S. R. Smith
,
L. Morgan
British Journal of Haematology
1996
Corpus ID: 25950745