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IL6R gene

Known as: INTERLEUKIN 6 RECEPTOR, CD126, INTERLEUKIN 6 RECEPTOR, ALPHA 
This gene in involved in the regulation of cellular responses; such as the immune response, hematopoiesis, and acute-phase inflammatory reactions.
National Institutes of Health

Related topics

Related topics

8 relations
Cytokine Signaling ProcessIL6R protein, humanIL6R wt AlleleIntercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Association of the IL6 rs1800796, but not of the IL6 rs1800795, IL6R rs4845617 and rs2228145 polymorphisms with hip fracture in elderly Mexican women
Background and aimsPolymorphisms in Interleukin-6 (IL6) and its receptor (IL6R) have been associated with bone mineral density… 
2017
2017
Expression and regulation of interleukin 6 and its receptor at the maternal-conceptus interface during pregnancy in pigs.
2016
2016
Hepatitis C virus suppresses Hepatocyte Nuclear Factor 4 alpha, a key regulator of hepatocellular carcinoma.
2015
2015
Association of a polymorphism of the interleukin 6 receptor gene with chronic kidney disease in Japanese individuals
Various loci and genes that confer susceptibility to coronary artery disease (CAD) have been identified in Caucasian populations… 
2014
2014
The effect of interleukin-1β, interleukin-6, and tumor necrosis factor-α on estradiol-17β release in the myometrium: the in vitro study on the pig model.
2012
2012
Abstract 2723: Sarilumab (REGN88), a fully-human anti-IL6R antibody, inhibits tumor growth in preclinical models, as a single agent and in combination with the VEGF blocker aflibercept
IL6 is a pro-inflammatory cytokine that is expressed in multiple cancer types. Clinical studies have shown that increased serum… 
2011
2011
Lack of association of IL6R rs2228145 and IL6ST/gp130 rs2228044 gene polymorphisms with cardiovascular disease in patients with rheumatoid arthritis.
Interleukin-6 (IL-6) is a key mediator of inflammation in rheumatoid arthritis (RA) and its actions may be controlled by the IL-6… 
2010
2010
Influence of IL6R rs8192284 Polymorphism Status in Disease Activity in Rheumatoid Arthritis
Objective. To analyze the influence of IL6R rs8192284 polymorphism on the disease activity of rheumatoid arthritis (RA). Methods… 
2003
2003
Identification of novel SNPs in the interleukin 6 receptor gene (IL6R)
The human interleukin‐6 receptor (IL6R) is responsible for signal transduction of IL6 that might have associations with immune… 
2001
2001
Protein kinase C delta and eta isoenzymes control the shedding of the interleukin 6 receptor alpha in myeloma cells.
The soluble interleukin 6 receptor alpha is an agonistic molecule of interleukin 6 (IL-6) and is important in the biology of… 
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