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Interleukin-12 Receptor beta 1 Subunit

Known as: CD212 Antigen, Interleukin-12 Receptor beta 1 Chain, IL-12R Subunit Beta-1 
Interleukin-12 receptor subunit beta-1 (662 aa, ~73 kDa) is encoded by the human IL12RB1 gene. This protein plays a role in interleukin-12 binding… 
National Institutes of Health

Related topics

Related topics

21 relations
Cytokine Receptor GeneCytokine Signaling ProcessIL12 Signaling PathwayIL12RB1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation.
2013
2013
Haplotypes of IL-12Rβ1 impact on the clinical phenotype of hidradenitis suppurativa.
2010
2010
Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans.
2009
2009
Induction of lymphotoxin‐α by interleukin‐12 p40 homodimer, the so‐called biologically inactive molecule, but not IL‐12 p70
Interleukin‐12 (IL‐12) p70 (p40:p35) is a bioactive cytokine and its biological functions are becoming clear. On the other hand… 
2008
2008
IL-12 RB1 Genetic Variants Contribute to Human Susceptibility to Severe Acute Respiratory Syndrome Infection among Chinese
Background Cytokines play important roles in antiviral action. We examined whether polymorphisms of interleukin (IL)-12 receptor… 
Highly Cited
2007
Highly Cited
2007
Associations between measles vaccine immunity and single-nucleotide polymorphisms in cytokine and cytokine receptor genes.
BACKGROUND Cytokines are key regulators of measles vaccine humoral and cellular immunity. Single-nucleotide polymorphisms (SNPs… 
Highly Cited
2005
Highly Cited
2005
Interleukin-12 receptor beta 1 chain deficiency in a child with disseminated tuberculosis.
An 11-year-old girl who presented with disseminated tuberculosis associated with secondary hemophagocytosis received a diagnosis… 
2004
2004
Inhaled IFN-γ for persistent nontuberculous mycobacterial pulmonary disease due to functional IFN-γ deficiency
Pulmonary infection with nontuberculous mycobacteria (NTM) in previously healthy human immunodeficiency virus-seronegative… 
2002
2002
Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages.
ATP-binding cassette (ABC) transporters are a large family of proteins whose role is to translocate various substances across… 
1998
1998
Interleukin-12 induces tyrosine phosphorylation of an 85-kDa protein associated with the interleukin-12 receptor beta 1 subunit.
Interleukin-12 (IL12) is a heterodimeric cytokine composed of p35 and p40 subunits and having multiple immunomodulatory effects… 
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