Interleukin-12 Receptor beta 1 Subunit

Known as: CD212 Antigen, Interleukin-12 Receptor beta 1 Chain, IL-12R Subunit Beta-1 
Interleukin-12 receptor subunit beta-1 (662 aa, ~73 kDa) is encoded by the human IL12RB1 gene. This protein plays a role in interleukin-12 binding… (More)
National Institutes of Health

Related topics

Related topics

21 relations
Cytokine Receptor GeneCytokine Signaling ProcessIL12 Signaling PathwayIL12RB1 gene
(More)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Nucleotide variation in IL-10 and IL-12 and their receptors and cervical and vulvar cancer risk: a hybrid case-parent triad and case-control study.
Given the important role of cell mediated immunity in viral clearance and control of premalignant lesions, we hypothesize that… (More)
  • table 2
  • table 2
  • table 4
Is this relevant?
2010
2010
Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans.
BACKGROUND The acute skin lesions of atopic dermatitis (AD) are associated with Th2 cells; however, the chronic skin lesions of… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • table 4
Is this relevant?
2009
2009
Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70.
Interleukin-12 (IL-12) p70 (p40:p35) is a bioactive cytokine and its biological functions are becoming clear. On the other hand… (More)
Is this relevant?
2007
2007
Role of Toll-like receptor 9 in Legionella pneumophila-induced interleukin-12 p40 production in bone marrow-derived dendritic cells and macrophages from permissive and nonpermissive mice.
The progression of Legionella pneumophila infection in macrophages is controlled by the Lgn1 gene locus, which expresses the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2007
2007
Associations between measles vaccine immunity and single-nucleotide polymorphisms in cytokine and cytokine receptor genes.
BACKGROUND Cytokines are key regulators of measles vaccine humoral and cellular immunity. Single-nucleotide polymorphisms (SNPs… (More)
  • figure 1
  • table 1
  • table 3
  • table 4
  • table 5
Is this relevant?
2006
2006
T cell-dependent activation of dendritic cells requires IL-12 and IFN-gamma signaling in T cells.
Patients presenting with genetic deficiencies in IFNGR1, IFNGR2, IL-12B, and IL-12RB1 display increased susceptibility to… (More)
Is this relevant?
2005
2005
Interleukin-12 receptor beta 1 chain deficiency in a child with disseminated tuberculosis.
An 11-year-old girl who presented with disseminated tuberculosis associated with secondary hemophagocytosis received a diagnosis… (More)
Is this relevant?
2002
2002
Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages.
ATP-binding cassette (ABC) transporters are a large family of proteins whose role is to translocate various substances across… (More)
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • figure 4
Is this relevant?
Review
2001
Review
2001
Mendelian susceptibility to mycobacterial infection in man.
Selective susceptibility to weakly pathogenic mycobacteria, such as bacillus Calmette-Guérin (BCG) vaccine and environmental non… (More)
  • figure 1
  • figure 2
Is this relevant?
1998
1998
Interleukin-12 induces tyrosine phosphorylation of an 85-kDa protein associated with the interleukin-12 receptor beta 1 subunit.
Interleukin-12 (IL12) is a heterodimeric cytokine composed of p35 and p40 subunits and having multiple immunomodulatory effects… (More)
Is this relevant?