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IL12RB1 gene

Known as: INTERLEUKIN 12 RECEPTOR, BETA-1, Interleukin 12 Receptor, Beta 1 Gene, interleukin 12 receptor subunit beta 1 
This gene plays a role in cellular signaling and is involved in immunity/defense.
National Institutes of Health

Related topics

Related topics

8 relations
Cytokine Signaling ProcessIntercellular Communication ProcessInterleukin-12 Receptor beta 1 SubunitLigand Binding

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IL12RB1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
IL12Rβ1: the cytokine receptor that we used to know.
2014
2014
STAT4 Gene Polymorphisms Are Associated with Susceptibility and ANA Status in Primary Biliary Cirrhosis
Recent genome-wide association studies suggest that genetic factors contribute to primary biliary cirrhosis (PBC) susceptibility… 
Review
2013
Review
2013
IL‐12Rβ1 Deficiency: Mutation Update and Description of the IL12RB1 Variation Database
IL‐12Rβ1 deficiency is an autosomal recessive disorder characterized by predisposition to recurrent and/or severe infections… 
Highly Cited
2012
Highly Cited
2012
Resequencing candidate genes implicates rare variants in asthma susceptibility.
Highly Cited
2010
Highly Cited
2010
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis
A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from… 
2010
2010
Cytokine genes are associated with tuberculin skin test response in a native Brazilian population.
Highly Cited
2008
Highly Cited
2008
Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells
The cytokines controlling the development of human interleukin (IL) 17–producing T helper cells in vitro have been difficult to… 
Highly Cited
2007
Highly Cited
2007
Association of polymorphisms in IL-12/IFN-gamma pathway genes with susceptibility to pulmonary tuberculosis in Indonesia.
Highly Cited
2005
Highly Cited
2005
Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes.
Atopic dermatitis (AD) is frequently associated with eosinophilia, highly elevated immunoglobulin E (IgE) levels and increased… 
Highly Cited
2004
Highly Cited
2004
Association of IL12RB1 polymorphisms with pulmonary tuberculosis in adults in Morocco.
Five disease-causing genes, including the IL12RB1 gene that encodes the beta 1 chain of the receptor for interleukin (IL)-12 (IL… 
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