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IL12RB1 gene
Known as:
INTERLEUKIN 12 RECEPTOR, BETA-1
, Interleukin 12 Receptor, Beta 1 Gene
, interleukin 12 receptor subunit beta 1
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This gene plays a role in cellular signaling and is involved in immunity/defense.
National Institutes of Health
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Related topics
Related topics
8 relations
Cytokine Signaling Process
Intercellular Communication Process
Interleukin-12 Receptor beta 1 Subunit
Ligand Binding
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Narrower (1)
IL12RB1 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Three novel compound heterozygous IL12RB1 mutations in Chinese patients with Mendelian susceptibility to mycobacterial disease
Xiaopei Zhou
,
Weimin Jia
,
+13 authors
Xianqin Zhang
PLoS ONE
2019
Corpus ID: 121655650
Mendelian Susceptibility to Mycobacterial Diseases (MSMD) is a primary immunodeficiency disease (PID) characterized by variable…
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2017
2017
Distinct Antigen Delivery Systems Induce Dendritic Cells’ Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis
Valerio Costa
,
D. Righelli
,
Francesco Russo
,
P. De Berardinis
,
C. Angelini
,
L. D’Apice
International Journal of Molecular Sciences
2017
Corpus ID: 10611899
Vaccination is the most successful and cost-effective method to prevent infectious diseases. However, many vaccine antigens have…
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2016
2016
Variations in IL-23 and IL-25 receptor gene structure, sequence and expression associated with the two disease forms of sheep paratuberculosis
L. Nicol
,
A. Gossner
,
C. Watkins
,
F. Chianini
,
R. Dalziel
,
J. Hopkins
Veterinary Research
2016
Corpus ID: 206985061
The immunopathology of paucibacillary and multibacillary sheep paratuberculosis is characterized by inflammatory T cell and…
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2015
2015
The introduction of RNA-DNA differences underlies interindividual variation in the human IL12RB1 mRNA repertoire
Amy J. Turner
,
P. Aggarwal
,
+4 authors
R. Robinson
Proceedings of the National Academy of Sciences…
2015
Corpus ID: 37138905
Significance The gene interleukin-12 receptor β1 (IL12RB1) regulates susceptibility to several human diseases, including…
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2014
2014
STAT4 Gene Polymorphisms Are Associated with Susceptibility and ANA Status in Primary Biliary Cirrhosis
S. Joshita
,
T. Umemura
,
+10 authors
M. Ota
Disease Markers
2014
Corpus ID: 18195123
Recent genome-wide association studies suggest that genetic factors contribute to primary biliary cirrhosis (PBC) susceptibility…
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2012
2012
Early Control of Mycobacterium tuberculosis Infection Requires il12rb1 Expression by rag1-Dependent Lineages
Halli E. Miller
,
R. Robinson
Infection and Immunity
2012
Corpus ID: 25189076
ABSTRACT IL12RB1 is essential for human resistance to Mycobacterium tuberculosis infection. In the absence of a functional…
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Highly Cited
2005
Highly Cited
2005
Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes.
N. Takahashi
,
M. Akahoshi
,
+13 authors
T. Shirakawa
Human Molecular Genetics
2005
Corpus ID: 14208895
Atopic dermatitis (AD) is frequently associated with eosinophilia, highly elevated immunoglobulin E (IgE) levels and increased…
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2005
2005
Interleukin 12 (IL12B), interleukin 12 receptor (IL12RB1) and interleukin 23 (IL23A) gene polymorphism in systemic lupus erythematosus.
E. Sánchez
,
S. Morales
,
+10 authors
J. Martín
Rheumatology
2005
Corpus ID: 23879788
OBJECTIVE The aim of this study was to assess the possible association between the interleukin-12B (IL12B) and interleukin-12…
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2005
2005
Interleukin 12 (IL12B) and interleukin 12 receptor (IL12RB1) gene polymorphisms in rheumatoid arthritis.
G. Orozco
,
M. González-Gay
,
+5 authors
Javier Martín
Human Immunology
2005
Corpus ID: 3189883
2003
2003
Missense mutations of the interleukin-12 receptor beta 1(IL12RB1) and interferon-gamma receptor 1 (IFNGR1) genes are not associated with susceptibility to lepromatous leprosy in Korea
Seong-Beom Lee
,
Byoung Chul Kim
,
+4 authors
G. Chae
Immunogenetics
2003
Corpus ID: 51695473
Interleukin-12 receptor beta 1 (IL12RB1), interleukin-12 receptor beta 2 (IL12RB2), and interferon gamma receptor 1 (IFNGR1…
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