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IL12RB1 gene

Known as: INTERLEUKIN 12 RECEPTOR, BETA-1, Interleukin 12 Receptor, Beta 1 Gene, interleukin 12 receptor subunit beta 1 
This gene plays a role in cellular signaling and is involved in immunity/defense.
National Institutes of Health

Related topics

Related topics

8 relations
Cytokine Signaling ProcessIntercellular Communication ProcessInterleukin-12 Receptor beta 1 SubunitLigand Binding
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IL12RB1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Cryptococcal osteomyelitis in a child with a novel compound mutation of the IL12RB1 gene.
The IL-12p40/IL-12Rbeta1 and IFN-gammaR1/IFN-gammaR2/STAT1 signaling pathways are important for clearing intracellular bacteria… Expand
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2012
2012
IL1B, IL4R, IL12RB1 and TNF gene polymorphisms are associated with Plasmodium vivax malaria in Brazil
BackgroundMalaria is among the most prevalent parasitic diseases worldwide. In Brazil, malaria is concentrated in the northern… Expand
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Highly Cited
2010
Highly Cited
2010
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis
A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from… Expand
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Highly Cited
2008
Highly Cited
2008
Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells
The cytokines controlling the development of human interleukin (IL) 17–producing T helper cells in vitro have been difficult to… Expand
2007
2007
Association of IL12RB1 polymorphisms with susceptibility to and severity of tuberculosis in Japanese: a gene‐based association analysis of 21 candidate genes
Tuberculosis (TB) is the second commonest cause of death from infectious disease after HIV/AIDS worldwide. Association studies… Expand
2005
2005
Interleukin 12 (IL12B), interleukin 12 receptor (IL12RB1) and interleukin 23 (IL23A) gene polymorphism in systemic lupus erythematosus.
OBJECTIVE The aim of this study was to assess the possible association between the interleukin-12B (IL12B) and interleukin-12… Expand
2005
2005
Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes.
Atopic dermatitis (AD) is frequently associated with eosinophilia, highly elevated immunoglobulin E (IgE) levels and increased… Expand
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2005
2005
Interleukin 12 (IL12B) and interleukin 12 receptor (IL12RB1) gene polymorphisms in rheumatoid arthritis.
The aim of this study was to assess the possible association between the IL12B and the IL12RB1 gene polymorphisms and the… Expand
Highly Cited
2004
Highly Cited
2004
Association of IL12RB1 polymorphisms with pulmonary tuberculosis in adults in Morocco.
Five disease-causing genes, including the IL12RB1 gene that encodes the beta 1 chain of the receptor for interleukin (IL)-12 (IL… Expand
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Review
2003
Review
2003
Genetic variations in the interleukin-12/interleukin-23 receptor (β1) chain, and implications for IL-12 and IL-23 receptor structure and function
Cell-mediated immunity (CMI) plays an essential role in human host defense against intracellular bacteria. Type-1 cytokines… Expand
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