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IL12RB1 gene

Known as: INTERLEUKIN 12 RECEPTOR, BETA-1, Interleukin 12 Receptor, Beta 1 Gene, interleukin 12 receptor subunit beta 1 
This gene plays a role in cellular signaling and is involved in immunity/defense.
National Institutes of Health

Related topics

Related topics

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Cytokine Signaling ProcessIntercellular Communication ProcessInterleukin-12 Receptor beta 1 SubunitLigand Binding

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IL12RB1 wt Allele

Papers overview

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2019
2019
Three novel compound heterozygous IL12RB1 mutations in Chinese patients with Mendelian susceptibility to mycobacterial disease
Mendelian Susceptibility to Mycobacterial Diseases (MSMD) is a primary immunodeficiency disease (PID) characterized by variable… 
2017
2017
Distinct Antigen Delivery Systems Induce Dendritic Cells’ Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis
Vaccination is the most successful and cost-effective method to prevent infectious diseases. However, many vaccine antigens have… 
2016
2016
Variations in IL-23 and IL-25 receptor gene structure, sequence and expression associated with the two disease forms of sheep paratuberculosis
The immunopathology of paucibacillary and multibacillary sheep paratuberculosis is characterized by inflammatory T cell and… 
2015
2015
The introduction of RNA-DNA differences underlies interindividual variation in the human IL12RB1 mRNA repertoire
Significance The gene interleukin-12 receptor β1 (IL12RB1) regulates susceptibility to several human diseases, including… 
2012
2012
Early Control of Mycobacterium tuberculosis Infection Requires il12rb1 Expression by rag1-Dependent Lineages
ABSTRACT IL12RB1 is essential for human resistance to Mycobacterium tuberculosis infection. In the absence of a functional… 
Highly Cited
2005
Highly Cited
2005
Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes.
Atopic dermatitis (AD) is frequently associated with eosinophilia, highly elevated immunoglobulin E (IgE) levels and increased… 
2005
2005
Interleukin 12 (IL12B), interleukin 12 receptor (IL12RB1) and interleukin 23 (IL23A) gene polymorphism in systemic lupus erythematosus.
OBJECTIVE The aim of this study was to assess the possible association between the interleukin-12B (IL12B) and interleukin-12… 
2005
2005
Interleukin 12 (IL12B) and interleukin 12 receptor (IL12RB1) gene polymorphisms in rheumatoid arthritis.
2003
2003
Missense mutations of the interleukin-12 receptor beta 1(IL12RB1) and interferon-gamma receptor 1 (IFNGR1) genes are not associated with susceptibility to lepromatous leprosy in Korea
Interleukin-12 receptor beta 1 (IL12RB1), interleukin-12 receptor beta 2 (IL12RB2), and interferon gamma receptor 1 (IFNGR1… 
2003
2003
Definition of polymorphisms in the gene encoding the interleukin-12 receptor B1 subunit: testing linkage disequilibrium with Type I diabetes susceptibility
The cytokine interleukin (IL)-12 is bound by a heterodimeric receptor and mediates a range of immunological activities, in… 
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