Integrins

Known as: Integrins [Chemical/Ingredient], Integrin, Extracellular Matrix, Integrins 
A family of transmembrane glycoproteins (MEMBRANE GLYCOPROTEINS) consisting of noncovalent heterodimers. They interact with a wide variety of ligands… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Ever since Stephen Paget’s 1889 hypothesis, metastatic organotropism has remained one of cancer’s greatest mysteries. Here we… (More)
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Highly Cited
2010
Highly Cited
2010
On page 17 of this article, in the section Targeting αvβ3 and αvβ5 the sentence at the start of the second paragraph that reads… (More)
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Review
2002
Review
2002
In their roles as major adhesion receptors, integrins signal across the plasma membrane in both directions. Recent structural and… (More)
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Review
2002
Review
2002
As cancer cells undergo metastasis — invasion and migration of a new tissue — they penetrate and attach to the target tissue's… (More)
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Review
1999
Review
1999
Cells reside in a protein network, the extracellular matrix (ECM), which they secrete and mold into the intercellular space. The… (More)
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Highly Cited
1997
Highly Cited
1997
We report here that living cells and nuclei are hard-wired such that a mechanical tug on cell surface receptors can immediately… (More)
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Review
1997
Review
1997
The loss of integrin-mediated cell-matrix contact induces apoptosis ('anoikis') in certain cell types. Recently it has been shown… (More)
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Review
1996
Review
1996
Proteins that contain the Arg-Gly-Asp (RGD) attachment site, together with the integrins that serve as receptors for them… (More)
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Review
1995
Review
1995
Integrins receive signals from other receptors that lead to activation of ligand binding (inside-out signaling) and matrix… (More)
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Highly Cited
1991
Highly Cited
1991
Rolling of leukocytes on vascular endothelial cells, an early event in inflammation, can be reproduced in vitro on artificial… (More)
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