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CD18 Antigens

Known as: Antigens, CD18, beta2 Integrin, Integrin, beta2 
Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (1)

CD Antigens
Complement component C4ITGB2 geneITGB2 wt AlleleIn Blood

Narrower (1)

Integrin Beta-2, human

Papers overview

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Highly Cited
2003
Highly Cited
2003
Acidic polysaccharide isolated from Phellinus linteus induces nitric oxide-mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C.
Highly Cited
2000
Highly Cited
2000
Effects of fluorescent dyes on selectin and integrin-mediated stages of adhesion and migration of flowing leukocytes.
Highly Cited
1996
Highly Cited
1996
A balance between nitric oxide and oxidants regulates mast cell-dependent neutrophil-endothelial cell interactions.
Nitric oxide (NO) synthesis inhibition causes neutrophil adhesion to endothelium via a mast cell- and oxidant-dependent mechanism… 
Highly Cited
1996
Highly Cited
1996
Heat shock protein 65 induces CD62e, CD106, and CD54 on cultured human endothelial cells and increases their adhesiveness for monocytes and granulocytes.
Expression of members of the heat shock protein 60 (hsp60) family in tissues has been reported to coincide with leukocyte… 
Highly Cited
1995
Highly Cited
1995
Improved transfer of the leukocyte integrin CD18 subunit into hematopoietic cell lines by using retroviral vectors having a gibbon ape leukemia virus envelope.
Leukocyte adherence deficiency (LAD) is an inherited immunodeficiency disease caused by defects in the CD18 leukocyte integrin… 
Highly Cited
1992
Highly Cited
1992
The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat.
Recently the critical requirement for the CD18 family of adhesion molecules on leucocytes for their adhesion and migration to… 
Highly Cited
1992
Highly Cited
1992
Stimulation of human naive and memory T helper cells with bacterial superantigen. Naive CD4+45RA+ T cells require a costimulatory signal mediated through the LFA-1/ICAM-1 pathway.
The role of the accessory molecule ICAM-1 in activation of subpopulations of human T cells was examined using the bacterial… 
Highly Cited
1992
Highly Cited
1992
Cross-linking of sialophorin (CD43) induces neutrophil aggregation in a CD18-dependent and a CD18-independent way.
Normal human neutrophils bound an as yet unclustered mAb designated BS-1. The Ag immunoprecipitated with BS-1 was blotted by CD43… 
Highly Cited
1991
Highly Cited
1991
Calcium signaling capacity of the CD11b/CD18 integrin on human neutrophils.
Highly Cited
1987
Highly Cited
1987
In vivo inhibition of neutrophil function in the rabbit using monoclonal antibody to CD18.
The CD11b/CD18 membrane antigen complex has been shown to be essential for normal neutrophil function in vitro, and patients… 
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