Inositol Phosphate Metabolism Pathway

Known as: Inositol Metabolism, Inositol Phosphate Metabolism, inositol phosphate metabolic process 
The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. [CHEBI… (More)
National Institutes of Health

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1-Phosphatidylinositol 4-KinaseAKT3 protein, humanINPP4B protein, humanInositol-Trisphosphate 3-Kinase C, Human
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Papers overview

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2015
2015
Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer
Members of the inositol phosphate metabolism pathway regulate cell proliferation, migration and phosphatidylinositol-3-kinase… (More)
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2002
2002
Simulations of inositol phosphate metabolism and its interaction with InsP(3)-mediated calcium release.
Inositol phosphates function as second messengers for a variety of extracellular signals. Ins(1,4,5)P(3) generated by… (More)
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Highly Cited
2002
Highly Cited
2002
Inositol pyrophosphates regulate endocytic trafficking.
The high energy potential and rapid turnover of the recently discovered inositol pyrophosphates, such as diphosphoinositol… (More)
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Highly Cited
2001
Highly Cited
2001
A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host cell actin cytoskeleton rearrangements and bacterial internalization.
A central feature of Salmonella pathogenicity is the bacterium's ability to enter into non-phagocytic cells. Bacterial… (More)
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Highly Cited
2000
Highly Cited
2000
Critical Evaluation of ECV304 as a Human Endothelial Cell Model Defined by Genetic Analysis and Functional Responses: A Comparison with the Human Bladder Cancer Derived Epithelial Cell Line T24/83
Early reports indicated that ECV304 was a spontaneously-transformed line derived from a Japanese human umbilical vein endothelial… (More)
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Highly Cited
1998
Highly Cited
1998
Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells.
Effects of antioxidants, resveratrol, quercetin, and N-acetylcysteine (NAC) on the functions of cultured rat hepatic stellate… (More)
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Highly Cited
1998
Highly Cited
1998
Regulation of cell-specific inositol metabolism and transport in plant salinity tolerance.
myo-Inositol and its derivatives are commonly studied with respect to cell signaling and membrane biogenesis, but they also… (More)
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Highly Cited
1996
Highly Cited
1996
Coordinate transcriptional induction of myo-inositol metabolism during environmental stress.
The pathway from glucose 6-phosphate (G 6-P) to myoinositol 1-phosphate (Ins 1-P) and myo-inositol (Ins) is essential for the… (More)
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Highly Cited
1992
Highly Cited
1992
The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase
LOWE'S oculocerebrorenal syndrome1–3 (OCRL) is a human X-linked developmental disorder of unknown pathogenesis4–8 and has a… (More)
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Highly Cited
1983
Highly Cited
1983
Polyol pathway activity and myo-inositol metabolism. A suggested relationship in the pathogenesis of diabetic neuropathy.
Two major metabolic perturbations, increased polyol (sorbitol) pathway activity and reduced tissue myo-inositol content, are… (More)
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