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1-Phosphatidylinositol 4-Kinase

Known as: PI4KBeta, PIK4CB, PtdIns 4 Kinase 
An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphatidylinositol 4-phosphate, the first committed step… 
National Institutes of Health

Related topics

Related topics

21 relations
1-Phosphatidylinositol-4-phosphate kinaseEndocytosisEnzyme GeneHomo sapiens

Papers overview

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Highly Cited
2005
Highly Cited
2005
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
During the evolution of metazoans and the rise of systemic hormonal regulation, the insulin-controlled class 1… 
Highly Cited
2004
Highly Cited
2004
Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane.
A critical early event in the HIV type 1 (HIV-1) particle assembly pathway is the targeting of the Gag protein to the site of… 
Highly Cited
2002
Highly Cited
2002
Targeting of Golgi-Specific Pleckstrin Homology Domains Involves Both PtdIns 4-Kinase-Dependent and -Independent Components
Highly Cited
2000
Highly Cited
2000
Activation by Cdc42 and Pip2 of Wiskott-Aldrich Syndrome Protein (Wasp) Stimulates Actin Nucleation by Arp2/3 Complex
We purified native WASp (Wiskott-Aldrich Syndrome protein) from bovine thymus and studied its ability to stimulate actin… 
Highly Cited
1999
Highly Cited
1999
Rac Homologues and Compartmentalized Phosphatidylinositol 4, 5-Bisphosphate Act in a Common Pathway to Regulate Polar Pollen Tube Growth
Pollen tube cells elongate based on actin- dependent targeted secretion at the tip. Rho family small GTPases have been implicated… 
Review
1998
Review
1998
Phosphoinositide kinases.
Phosphatidylinositol, a component of eukaryotic cell membranes, is unique among phospholipids in that its head group can be… 
Review
1996
Review
1996
From Form to Function: Signaling by Protein Tyrosine Phosphatases
Highly Cited
1994
Highly Cited
1994
Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose
We identified four polypeptides of 47, 44, 40, and 35 kD that bind to profilin-Sepharose and elute with high salt. When purified… 
Review
1993
Review
1993
The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors.
GPI STRUCTURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 ATTACHMENT OF THE GPI TO… 
Highly Cited
1993
Highly Cited
1993
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis.
The glycosylphosphatidylinositol (GPI) anchor is a membrane attachment structure of many proteins and occurs in a wide variety of… 
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