1-Phosphatidylinositol 4-Kinase

Known as: PI4KBeta, PIK4CB, PtdIns 4 Kinase 
An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphatidylinositol 4-phosphate, the first committed step… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Host factor pathways are known to be essential for hepatitis C virus (HCV) infection and replication in human liver cells. To… (More)
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Highly Cited
2008
Highly Cited
2008
Small molecule inhibitors of HER2 are clinically active in women with advanced HER2-positive breast cancer who have progressed on… (More)
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Highly Cited
2005
Highly Cited
2005
During the evolution of metazoans and the rise of systemic hormonal regulation, the insulin-controlled class 1… (More)
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Highly Cited
2005
Highly Cited
2005
Protein kinase D (PKD) regulates the fission of vesicles originating from the trans-Golgi network. We show that… (More)
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Highly Cited
2003
Highly Cited
2003
Phosphatidylinositol 4 phosphate [PI(4)P] is essential for secretion in yeast, but its role in mammalian cells is unclear… (More)
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Highly Cited
2001
Highly Cited
2001
Autophagy is an intracellular bulk protein degradation system. Beclin is known to be involved in this process; however, its role… (More)
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Highly Cited
1999
Highly Cited
1999
To examine the mechanism by which free fatty acids (FFA) induce insulin resistance in human skeletal muscle, glycogen, glucose-6… (More)
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Highly Cited
1999
Highly Cited
1999
Pollen tube cells elongate based on actin- dependent targeted secretion at the tip. Rho family small GTPases have been implicated… (More)
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Review
1998
Review
1998
Phosphatidylinositol, a component of eukaryotic cell membranes, is unique among phospholipids in that its head group can be… (More)
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Highly Cited
1995
Highly Cited
1995
The synthesis of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2], the immediate precursor of intracellular signals… (More)
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