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ITIM

Known as: Immunoreceptor Tyrosine-Based Inhibitory Motif 
ITIM (immunoreceptor Tyr-based inhibition motif) (I/V-X-Y-X-X-L), a protein domain involved in STP, binds to SH2 domain in SHP1 and SHP2, e.g., in… 
National Institutes of Health

Related topics

Related topics

13 relations
CD22 protein, humanCD33 protein, humanErythropoietin ReceptorFCRL1 protein, human

Papers overview

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Review
2017
Review
2017
Relationship between FcγRIIB gene polymorphisms , periodontitis and adverse pregnancy outcomes in pregnant women
Background: FcγRIIb acts as a negative feedback regulator by inhibiting B-cell antigen receptor-elicited activation signals… 
2014
2014
Ig-like Receptor in Human NK Cells Endocytosis of an Inhibitory Killer Cell The AP-2 Clathrin Adaptor Mediates
CampbellOshinsky, Ashley M. James, Ilya Serebriiskii and Kerry S. Amanda K. Purdy, Diana A. Alvarez Arias, Jenniferol.1303406http… 
2012
2012
Microglial carbohydrate-binding receptors for neural repair
Microglia are the resident immune cells of the central nervous system (CNS) and perform typical scavenging and innate immune… 
2010
2010
Antagonizing inhibition gets NK cells going
Natural killer (NK) cells are key players in the innate immune system that provide rapid responses through cytokine secretion and… 
2009
2009
The Inhibitory Receptor FcgRIIB Is Overexpressed, and Its Ligation by Anti- FcgRIIB Antibodies Suppresses IgM Production and Induces Apoptosis in Waldenstrom's Macroglobulinemia.
Abstract 3736 Poster Board III-672 Introduction Waldenstrom9s macroglobulinemia (WM) is a lymphoplasmacytic lymphoma… 
2004
2004
Nouveaux acteurs de l’immunité innée : les récepteurs TREM
innee (cellules presentatrices d’antigenes, cellules natural killer [NK], polynucleaires neutrophiles) ont pour mission de… 
Review
2001
Review
2001
The receptors regulating natural cytotoxic effector functions.
Natural cytotoxic effector functions are regulated by a multitude of opposing signals provided by immunoglobulin and lectin-like… 
Review
1999
Review
1999
How to Extinguish Lymphocyte Activation, Immunotyrosine-Based Inhibition Motif (ITIM)-Bearing Molecules a Solution?
Abstract ITIM-bearing molecules represent a novel family of inhibitory receptors expressed widely through the hematopoietic… 
1998
1998
Receptor I-Associated lyn-Dependent Phosphorylation of Fc g Receptor IIB During Negative Regulation of Mast Cell Activation 1
FcgRIIB are low-affinity receptors for IgG whose intracytoplasmic domain contains an immunoreceptor tyrosine-based inhibition… 
1996
1996
The Ly-49 D Receptor Activates Murine Natural Killer Cells
  • 1996
  • Corpus ID: 20105034
Proteins encoded by members of the Ly-49 gene family are predominantly expressed on murine natural killer (NK) cells. Several… 
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