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ITIM
Known as:
Immunoreceptor Tyrosine-Based Inhibitory Motif
ITIM (immunoreceptor Tyr-based inhibition motif) (I/V-X-Y-X-X-L), a protein domain involved in STP, binds to SH2 domain in SHP1 and SHP2, e.g., in…
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National Institutes of Health
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Related topics
Related topics
13 relations
CD22 protein, human
CD33 protein, human
Erythropoietin Receptor
FCRL1 protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Relationship between FcγRIIB gene polymorphisms , periodontitis and adverse pregnancy outcomes in pregnant women
Yanming Wang
,
N. Sugita
,
+5 authors
L. Bi
2017
Corpus ID: 37455534
Background: FcγRIIb acts as a negative feedback regulator by inhibiting B-cell antigen receptor-elicited activation signals…
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2013
2013
ITIM proteins : a novel lymphomagenic feed-forward loop The Myc-miR-1792 axis amplifies B-cell receptor signaling via inhibition of
James N. Psathas
,
Patrick J. Doonan
,
Pichai Raman
,
B. Freedman
,
A. Minn
,
A. Thomas-Tikhonenko
2013
Corpus ID: 207881534
The c-Myc oncoprotein regulates greater than 15% of the human transcriptome and a limited number of microRNAs. Here we establish…
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2012
2012
Microglial carbohydrate-binding receptors for neural repair
Bettina Linnartz
,
L. Bodea
,
H. Neumann
Cell and Tissue Research
2012
Corpus ID: 253974679
Microglia are the resident immune cells of the central nervous system (CNS) and perform typical scavenging and innate immune…
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2010
2010
Antagonizing inhibition gets NK cells going
S. Rajagopalan
,
Eric O Long
Proceedings of the National Academy of Sciences…
2010
Corpus ID: 30793410
Natural killer (NK) cells are key players in the innate immune system that provide rapid responses through cytokine secretion and…
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2009
2009
The Inhibitory Receptor FcgRIIB Is Overexpressed, and Its Ligation by Anti- FcgRIIB Antibodies Suppresses IgM Production and Induces Apoptosis in Waldenstrom's Macroglobulinemia.
Guang Yang
,
P. Gong
,
+14 authors
S. Treon
2009
Corpus ID: 208397070
Abstract 3736 Poster Board III-672 Introduction Waldenstrom9s macroglobulinemia (WM) is a lymphoplasmacytic lymphoma…
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2004
2004
Nouveaux acteurs de l’immunité innée : les récepteurs TREM
S. Gibot
2004
Corpus ID: 85097840
innee (cellules presentatrices d’antigenes, cellules natural killer [NK], polynucleaires neutrophiles) ont pour mission de…
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Review
2002
Review
2002
LIR9, an Ig -superfamily activating receptor, is expressed as a
L. Borges
,
M. Kubin
,
T. Kuhlman
2002
Corpus ID: 81217497
LIRs are immunoglobulin-like receptors that have both activating and inhibitory functions in leukocytes. Here we report the…
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Review
2001
Review
2001
The receptors regulating natural cytotoxic effector functions.
M. Nikolova
,
L. Boumsell
,
A. Bensussan
Archivum Immunologiae et Therapiae Experimentalis
2001
Corpus ID: 36464578
Natural cytotoxic effector functions are regulated by a multitude of opposing signals provided by immunoglobulin and lectin-like…
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1999
1999
Differential Roles of Nand C-Terminal Immunoreceptor Tyrosine-Based Inhibition Motifs During Inhibition of Cell Activation by Killer Cell Inhibitory Receptors 1
P. Bruhns
,
P. Marchetti
,
W. Fridman
,
É. Vivier
,
M. Daëron
1999
Corpus ID: 37701899
Killer cell inhibitory receptors (KIRs) inhibit NK and T cell cytotoxicity when recognizing MHC class I molecules on target cells…
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1998
1998
Receptor I-Associated lyn-Dependent Phosphorylation of Fc g Receptor IIB During Negative Regulation of Mast Cell Activation 1
O. Malbec
,
D. Fong
,
+4 authors
M. Daëron
1998
Corpus ID: 15329777
FcgRIIB are low-affinity receptors for IgG whose intracytoplasmic domain contains an immunoreceptor tyrosine-based inhibition…
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