CD22 protein, human

Known as: CD22, Sialic Acid-Binding Ig-Like Lectin 2, Lyb8 
Cell surface carbohydrate molecules of the Lewis Y or Lewis X type that are detectable with monoclonal antibody B3. This group of antigens is found… (More)
National Institutes of Health

Related topics

Related topics

17 relations
B Cell Receptor Signaling PathwayB-LymphocytesCD22 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD22 Expressing Cell Count
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Broader (1)

CD22 antigen

Papers overview

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2018
2018
Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.
Lectins expressed on the cell surface are often bound and regulated by the membrane molecules containing the glycan ligands on… (More)
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2010
2010
CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells.
CD22 is a member of the sialic acid-binding Ig-like lectin (Siglec) family that is known to be a regulator of B cell signaling… (More)
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2009
2009
Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation.
CD22 is an inhibitory coreceptor on the surface of B cells that attenuates B cell antigen receptor (BCR) signaling and, therefore… (More)
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2002
2002
Difference in CD22 molecules in human B cells and basophils.
OBJECTIVE CD22 is believed to be restricted to normal and neoplastic B cells. Human basophils were found to express CD22… (More)
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Review
1997
Review
1997
CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling.
The development of B lymphocytes is a highly regulated process that depends in part on lineage-specific cell surface molecules… (More)
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1996
1996
Differential expression of CD22 (Lyb8) on murine B cells.
Previous studies have established the distribution, biochemistry and functional attributes of human CD22, a B cell-restricted… (More)
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Highly Cited
1994
Highly Cited
1994
Modifications of cell surface sialic acids modulate cell adhesion mediated by sialoadhesin and CD22
An increasing number of mammalian cell adhesion molecules, including sialoadhesion, CD22 and the family of selectins, have been… (More)
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1989
1989
Isolation and immunological characterization of a group of new B lymphomas from CBA mice.
We have isolated and characterized a new series of B lymphoma which occurred spontaneously in a group of CBA/N mice that were… (More)
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1987
1987
Ly1+ PRO-B lymphocyte clones. Phenotype, growth requirements and differentiation in vitro and in vivo.
Several clones obtained from the bone marrow of a BALB/c mouse were found to contain the heavy and light chain Ig genes in the… (More)
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1986
1986
Selective killing of normal and neoplastic human B cells with anti-CD19- and anti-CD22-ricin A chain immunotoxins.
Monoclonal antibodies directed against two human B cell-restricted antigens, CD19 and CD22, were conjugated to highly purified… (More)
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