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IL6ST gene

Known as: GP130 TRANSDUCER CHAIN, Interleukin 6 Signal Transducer (GP130, Oncostatin M Receptor) Gene, INTERLEUKIN 6 SIGNAL TRANSDUCER 
This gene plays a role in signal transduction and is putatively involved in embryonic development.
National Institutes of Health

Related topics

Related topics

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Cytokine SignalingIL6ST protein, humanSignal Transductiongp130 activity

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IL6ST wt Allele

Papers overview

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2020
2020
Interleukin 6 trans-signalling : cardiovascular risk marker or therapeutical target?
Background: Interleukin (IL) 6 signals in two pathways. In classical signalling, essential in antimicrobial defence and tissue… 
2015
2015
Characterization and localization of intracellular signals emanating from an oncogenic mutant of the cytokine receptor Gp130
2013
2013
Novel Small Molecules Disabling the IL-6/IL-6R/GP130 Heterohexamer Complex
Abstract : Interleukin-6 (IL-6) is a key signaling molecule in breast cancer cells. It is responsible for many cellular responses… 
2012
2012
IL-6 and IL-11 as Markers for Tumor Aggressiveness and Prognosis in Gastric Adenocarcinoma Patients without Mutations in Gp 130 Subunits
Background & Aims. A point mutation (gp130Y757F/ Y759F) was identified as being responsible for aberrant activation of gp130 in… 
2012
2012
Aplicación del protocolo OGC Puck para instrumentación lug and playRS232 y TCPIP
In the small market of precision measuring instruments there is no standardization of the communication protocols used for… 
2011
2011
T cells in Rheumatoid Arthritis
Identification of the role of T cells and their interaction with other cell types remains a major challenge to our understanding… 
2011
2011
O 1 . 2 Loss of the tumor suppressor CYLD causes enhanced NF-kappaB and Wnt / β-catenin signaling in multiple myeloma
Cytokine receptors exist in membrane bound and soluble form. While most soluble receptors are antagonists, some soluble receptors… 
2008
2008
Gp130 in Makrophagen und Granulozyten ist protektiv in der Concanavalin A-induzierten Hepatitis der Maus
2003
2003
In vivo functional analysis of gp130 in the development of cerebral cortex(Encouragement Award of the Japanese Teratology Society)(Japanese Teratology Society 43rd Annual Meeting)