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IL6ST protein, human

Known as: Interleukin Receptor Beta Chain, CDw130 antigen, CD130 protein, human 
Widely expressed (not restricted to IL6 responsive cells) by human IL6ST Gene (Type I Cytokine Receptor 2 Family), heterodimeric type I membrane… 
National Institutes of Health

Related topics

Related topics

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Broader (1)

Cytokine Receptor gp130
Cytokine SignalingIL6ST geneOncostatin-M Specific Receptor Beta SubunitSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Abstract P6-16-04: IL6ST, a biomarker of endocrine therapy response, has potential in identifying a subgroup of women with ER+ DCIS who are more likely to benefit from adjuvant endocrine therapy
Background: Ductal carcinoma in situ (DCIS) lesions are non-obligate precursors to invasive breast cancer (IBC). With the… 
2014
2014
Low incidence of IL6ST (gp130) mutations in exon 6 in lung cancer of a Chinese cohort.
2013
2013
Protein-protein interaction and SNP analysis in intraductal papillary mucinous neoplasm.
2013
2013
THU0174 Impact of IL-6R and IL-6ST Polymorphisms on Response to Anti-TNF Therapy in UK Patients – Results from the Braggss Cohort
Background Anti-tumour necrosis factor (anti-TNF) biologic therapy is a highly effective yet expensive treatment for patients… 
2008
2008
Cytokines in Metabolic Functions
During infections, circulating cytokines are largely produced by immune cells. In healthy obese individuals, large parts of these… 
1998
1998
Dimerization and activation of the common transducing chain (gp130) of the cytokines of the IL-6 family by mAb.
The objective of our research was to study the mechanisms of activation of mAb against the gp130 transducer chain common to the… 
Highly Cited
1996
Highly Cited
1996
Functional Expression of Soluble Human Interleukin-11 (IL-11) Receptor α and Stoichiometry of in Vitro IL-11 Receptor Complexes with gp130*
The interleukin-6 (IL-6) family of cytokines activates signaling through the formation of either gp130 homodimers, as for IL-6… 
1995
1995
Human gp130 transducer chain gene (IL6ST) is localized to chromosome band 5q11 and possesses a pseudogene on chromosome band 17p11.
Human gp130 (IL6ST) is one of the most widely used chains of the cytokine receptor family. Indeed, it is involved in signal… 
1994
1994
Establishment of the ELISA for murine soluble gp130, a signal transducer for the IL-6 family cytokine, and its detection in the ascitic fluids of tumor-bearing mice.
Interleukin-6 (IL-6) signal is transduced through a membrane glycoprotein gp130, which associates with the IL-6 receptor alpha… 
1992
1992
Chromosomal localization of the IL-6 receptor signal transducing subunit, gp130 (IL6ST)
Signal transduction in eukaryotic cells is a complex process mediated, normally, by the interaction of soluble extrinsic protein… 
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