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IL31 protein, human

Known as: interleukin 31, human, IL-31 protein, human, Interleukin-31 
Interleukin-31 (164 aa, ~18 kDa) is encoded by the human IL31 gene. This protein is involved in signaling during the immune response.
National Institutes of Health

Related topics

Related topics

12 relations
Cell Proliferation Regulatory ProcessCytokine GeneCytokine Receptor BindingCytokine Signaling

Broader (1)

Interleukins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Serum interleukin-31 level and pruritus in atopic dermatitis: A Meta-analysis.
OBJECTIVE To investigate associations of interleukin-31 (IL-31) and pruritus in atopic dermatitis (AD) with Meta-analysis… 
2017
2017
Natalizumab Changes the Peripheral Profile of the Th17 Panel in MS Patients: New Mechanisms of Action.
INTRODUCTION Natalizumab (NAT) is an effective treatment for relapsing remitting multiple sclerosis (RRMS), as it makes the blood… 
2015
2015
IL-31 and IL-33 circulating levels in allergic contact dermatitis.
Enhanced IL-31 expression in skin biopsies is present in allergic contact dermatitis (ACD). IL-33 expression is induced in… 
2014
2014
IL-31 Associated with Coronary Artery Lesion Formation in Kawasaki Disease
Background Kawasaki disease (KD) is known to be associated with T help (Th) 2 reaction and subsequently allergic diseases… 
Review
2013
Review
2013
Potential new therapeutic targets for pathological pruritus.
Very few approved medications are indicated for the treatment of pruritus, and drug development for pruritic diseases is awaited… 
2013
2013
Correlation between serum interleukin-31 level and the severity of disease in children with atopic dermatitis
Introduction Atopic dermatitis (AD) is a chronic inflammatory skin disease, characterized by intense itch, typical localization… 
Review
2013
Review
2013
Investigational drugs for pruritus
Introduction: Chronic pruritus (CP), defined as itch lasting for > 6 weeks, is a burdensome symptom of several different diseases… 
2011
2011
An H1‐histamine receptor antagonist decreases serum interleukin‐31 levels in patients with atopic dermatitis
MADAM, Atopic dermatitis (AD) is an intractable inflammatory skin disease characterized by an intensely pruritic skin rash with a… 
2010
2010
Interferon‐γ induces upregulation and activation of the interleukin‐31 receptor in human dermal microvascular endothelial cells
Abstract:  Interleukin‐31 (IL‐31), a recently discovered cytokine derived from T helper cells, is involved in chronic dermatitis… 
2006
2006
Three Dileucine-like Motifs within the Interbox1/2 Region of the Human Oncostatin M Receptor Prevent Efficient Surface Expression in the Absence of an Associated Janus Kinase*
The oncostatin M receptor (OSMR) is part of receptor complexes for oncostatin M and interleukin-31. Signaling events are… 
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