IL31 protein, human

Known as: interleukin 31, human, IL-31 protein, human, Interleukin-31 
Interleukin-31 (164 aa, ~18 kDa) is encoded by the human IL31 gene. This protein is involved in signaling during the immune response.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2018
010203020042018

Papers overview

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2012
2012
BACKGROUND Atopic dermatitis (AD) is an inflammatory skin disease affecting 10% to 20% of children and 1% to 3% of adults in… (More)
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2010
Highly Cited
2010
In addition to their microbiocidal properties, human beta-defensins (hBDs) and cathelicidin LL-37 stimulate a number of mammalian… (More)
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2009
Highly Cited
2009
BACKGROUND Interleukin-31 (IL-31), a novel cytokine, is upregulated in atopic dermatitis skin lesions in humans and skin lesions… (More)
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2007
2007
Lung epithelial cells are primary targets of oncostatin M (OSM) and, to a lower degree, of interleukin (IL)-6 and IL-31, all… (More)
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2007
2007
Interleukin (IL)-31 is mainly produced by CD4+ T cells, in particular T cells skewed toward a Th2 phenotype. Here we report for… (More)
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2007
2007
Interleukin-31 (IL-31) is a novel T-helper-lymphocyte-derived cytokine that plays an important role in allergic skin inflammation… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND IL-31 is a novel T-cell-derived cytokine that induces severe pruritus and dermatitis in transgenic mice, and signals… (More)
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2006
Highly Cited
2006
BACKGROUND IL-31 is produced by activated T lymphocytes, preferentially by TH2 cells. Transgenic mice overexpressing IL-31 have a… (More)
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2006
2006
Pruritus is an important symptom in atopic dermatitis (AD), but the major pruritogen has not been identified. NC/Nga mice… (More)
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2005
2005
To search for the pruritogen of atopic dermatitis, a characteristic symptom in atopic dermatitis patients, we examined… (More)
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