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Existence of capsaicin‐sensitive glutamatergic terminals in rat hypothalamus
CAPSAICIN has been suggested to act not only on thin primary afferents but also on the hypothalamus, but the neurotransmitter(s) of central capsaicin-sensitive neurons are unknown. The present studyExpand
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Scratching behavior induced by pruritogenic but not algesiogenic agents in mice.
We compared the behavioral effects of treatment with pruritogenic and algesiogenic agents in mice. The animals were given subcutaneous injections of pruritogenic agents, compound 48/80 (3-100Expand
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Direct action of immunoglobulin G on primary sensory neurons through Fc gamma receptor I
  • T. Andoh, Y. Kuraishi
  • Medicine, Biology
  • FASEB journal : official publication of the…
  • 1 January 2004
Immunoglobulin G (IgG) binds specific antigens, and IgG‐antigen complexes primarily activate immune cells and the complement system. These immune reactions are known to affect neural functionsExpand
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Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice
Serotonin (5-HT) is pruritogenic in humans and suggested to be involved in some pruritic diseases. Our experiments were carried out to determine whether an intradermal injection of 5-HT would elicitExpand
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Itch-associated response induced by experimental dry skin in mice.
The present study was conducted to establish a new mouse model of dry skin pruritus. The rostral back was treated daily with cutaneous application of acetone/ether (1:1) mixture (AE), water followingExpand
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Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice.
Our experiments were conducted to determine whether substance P (SP) would elicit an itch sensation mediated by mast cells in mice. An intradermal injection of SP (10-135 microgram site-1) into theExpand
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Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice.
The pruritogenic potency of tryptase and its involvement in anti-pruritic effect of intravenous nafamostat mesilate (NFM) were studied in mice. An intradermal injection of tryptase (0.05-1 ng/site)Expand
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Nociceptin gene expression in rat dorsal root ganglia induced by peripheral inflammation
NOCICEPTIN has been suggested to be involved in nociceptive processing in the spinal dorsal horn. To investigate whether the biosynthesis of nociceptin is altered in animals with nociceptiveExpand
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Involvement of increased expression of transient receptor potential melastatin 8 in oxaliplatin-induced cold allodynia in mice
Oxaliplatin is a chemotherapy drug and induces peripheral neuropathy which is aggravated by exposure to cold, the mechanism of which is unclear. In the present study, we investigated in mice whetherExpand
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Potential ability of morphine to inhibit the adhesion, invasion and metastasis of metastatic colon 26-L5 carcinoma cells.
Morphine is frequently used for cancer patient's terminal medical care to relieve cancer pain. In the present study, we examined the inhibitory effect of morphine on experimental lung metastasis andExpand
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