IFNGR2 gene

Known as: INTERFERON-GAMMA RECEPTOR, ACCESSORY FACTOR FOR, AF-1, IFGR2 
This gene is involved in receptor-mediated signal transduction in the interferon gamma signaling pathway and mediates innate immune responses.
National Institutes of Health

Papers overview

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2013
2013
Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare syndrome, the known genetic etiologies of which impair the… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND T-cell large granular lymphocytic leukemia is a rare lymphoproliferative disorder characterized by the expansion of… (More)
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Highly Cited
2009
Highly Cited
2009
Asthma, atopy, and related phenotypes are heterogeneous complex traits, with both genetic and environmental risk factors… (More)
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Review
2008
Review
2008
Primary immunodeficiencies (PIDs) were long thought to be exclusively recessive traits -- autosomal recessive (AR) in most cases… (More)
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Review
2008
Review
2008
Interferon (IFN) was originally identified as a substance 'interfering' with viral replication in vitro. The first IFNs to be… (More)
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Review
2007
Review
2007
The type I interferon (IFN)2 receptor (IFNAR) is comprised, as other cytokine receptors, of multiple components, in this case… (More)
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Highly Cited
2007
Highly Cited
2007
Helicobacter pylori infection, the dominant risk factor for gastric cancers, has been shown to elicit T helper type 1 (Th1… (More)
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Highly Cited
2006
Highly Cited
2006
RATIONALE Interferon-gamma (IFN-gamma) is of central interest in the study of tuberculosis. A number of single-gene mutations… (More)
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2002
2002
In the last 6 years, considerable advances have been made in the molecular analysis of a rare clinical syndrome: Mendelian… (More)
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1998
1998
To study the role of the interferon- (IFN) gammaR2 chain in IFN-gamma signaling and immune function, IFN-gammaR2-deficient mice… (More)
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