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IFNGR2 protein, human

Known as: IFN-Gamma-R2, Interferon Gamma Receptor Accessory Factor-1, IFN-Gamma Receptor 2 
Interferon gamma receptor 2 (337 aa, ~38 kDa) is encoded by the human IFNGR2 gene. This protein is involved in interferon gamma-dependent signaling.
National Institutes of Health

Related topics

Related topics

18 relations
Antiviral ResponseCytokine Receptor GeneCytokine Signaling ProcessIFNGR2 gene
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Broader (1)

Interferon Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A Novel Splice Site Mutation in IFNGR2 in Patients With Primary Immunodeficiency Exhibiting Susceptibility to Mycobacterial Diseases
Primary immunodeficiency (PID) refers to a group of heterogeneous genetic disorders with a weakened immune system. Mendelian… 
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Highly Cited
2011
Highly Cited
2011
Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators
The estrogen receptor (ER) is a ligand-dependent transcription factor containing two transcriptional activation domains. AF-1 is… 
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Review
2010
Review
2010
Safety, Tolerability, and Immunogenicity of Interferons
Interferons (IFNs) are class II cytokines that are key components of the innate immune response to virus infection. Three IFN sub… 
Highly Cited
2008
Highly Cited
2008
Human papillomavirus genotypes and HPV16 variants in penile carcinoma
The causative role of human papillomaviruses (HPV) and HPV16 variants has been extensively studied in uterine cervix dysplastic… 
2008
2008
Complementation of a pathogenic IFNGR2 misfolding mutation with modifiers of N-glycosylation
Germline mutations may cause human disease by various mechanisms. Missense and other in-frame mutations may be deleterious… 
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2005
2005
Investigation of genes coding for inflammatory components in Parkinson's disease
Several findings obtained recently indicate that inflammation may contribute to the pathogenesis in Parkinson's disease (PD… 
2004
2004
Alteration of gene expression profiles of peripheral mononuclear blood cells by tobacco smoke: implications for periodontal diseases.
Alterations of the host response by tobacco smoke adversely affect the periodontium. In this study, we examined the effects of in… 
Highly Cited
2004
Highly Cited
2004
Analysis of human papillomavirus type‐16 variants in Italian women with cervical intraepithelial neoplasia and cervical cancer
Human papillomavirus type 16 (HPV‐16) classes (E, AA, As, Af1, Af2) and their variants have different geographic distribution and… 
2003
2003
IGF-1 down-regulates IFN-gamma R2 chain surface expression and desensitizes IFN-gamma/STAT-1 signaling in human T lymphocytes.
The ability of insulin-like growth factor-1 (IGF-1) to regulate surface expression of the interferon-gamma receptor 2 (IFN-gamma… 
Highly Cited
1995
Highly Cited
1995
Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells.
The ability of interferon gamma (IFN-gamma) to inhibit the proliferation of type 2 T helper cells (TH2), but not that of type 1… 
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