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Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report
In this 4th edition of the Maastricht consensus report aspects related to the clinical role of H pylori were looked at again in 2010, with recommendations to guide doctors involved in the management of this infection associated with various clinical conditions.
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
This fifth edition of the Maastricht Consensus Report describes how experts from 24 countries examined new data related to H. pylori infection in the various clinical scenarios and provided recommendations on the basis of the best available evidence and relevance.
Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
H pylori eradication is less effective than proton pump inhibitor (PPI) treatment in preventing ulcer recurrence in long term NSAID users and a test and treat strategy using a non-invasive test is recommended in adult patients with persistent dyspepsia under the age of 45.
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
It is reported that interleukin-1 gene cluster polymorphisms suspected of enhancing production of interleucine-1-beta are associated with an increased risk of both hypochlorhydria induced by H. pylori and gastric cancer.
Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment.
Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms.
Timing of the Last Glacial Maximum from observed sea-level minima
IBD—what role do Proteobacteria play?
- I. Mukhopadhya, R. Hansen, E. El-Omar, G. Hold
- BiologyNature Reviews Gastroenterology &Hepatology
- 1 April 2012
It is postulated that Proteobacteria with adherent and invasive properties might exploit host defenses, drive proinflammatory change, alter the intestinal microbiota in favor of dysbiosis and ultimately lead to the development of IBD.
Kyoto global consensus report on Helicobacter pylori gastritis
A global consensus for gastritis was developed for the first time, which will be the basis for an international classification system and for further research on the subject.
Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?
- G. Hold, Megan Smith, C. Grange, Euan Watt, E. El-Omar, I. Mukhopadhya
- Biology, MedicineWorld Journal of Gastroenterology
- 7 February 2014
Advances in the understanding of microbial involvement in IBD pathogenesis over the past 10 years are reviewed and insight is offered into how this will shape the therapeutic management of the disease in the coming years.