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Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report
TLDR
In this 4th edition of the Maastricht consensus report aspects related to the clinical role of H pylori were looked at again in 2010, with recommendations to guide doctors involved in the management of this infection associated with various clinical conditions. Expand
Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
TLDR
H pylori eradication is less effective than proton pump inhibitor (PPI) treatment in preventing ulcer recurrence in long term NSAID users and a test and treat strategy using a non-invasive test is recommended in adult patients with persistent dyspepsia under the age of 45. Expand
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
TLDR
It is reported that interleukin-1 gene cluster polymorphisms suspected of enhancing production of interleucine-1-beta are associated with an increased risk of both hypochlorhydria induced by H. pylori and gastric cancer. Expand
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
TLDR
This fifth edition of the Maastricht Consensus Report describes how experts from 24 countries examined new data related to H. pylori infection in the various clinical scenarios and provided recommendations on the basis of the best available evidence and relevance. Expand
Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms.
TLDR
A proinflammatory cytokine genetic profile increases the risk of noncardia gastric adenocarcinoma but not other upper gastrointestinal cancers, possibly by inducing a hypochlorhydric and atrophic response to gastric H. pylori infection. Expand
Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment.
TLDR
Data suggest that, through recruitment of tumor-infiltrating immune cells, fusobacteria generate a proinflammatory microenvironment that is conducive for colorectal neoplasia progression, and this work finds that F.nucleatum does not exacerbate colitis, enteritis, or inflammation-associated intestinal carcinogenesis. Expand
IBD—what role do Proteobacteria play?
TLDR
It is postulated that Proteobacteria with adherent and invasive properties might exploit host defenses, drive proinflammatory change, alter the intestinal microbiota in favor of dysbiosis and ultimately lead to the development of IBD. Expand
Host-bacterial interactions in Helicobacter pylori infection.
TLDR
This review offers an insight into H pylori host-bacterial interactions, a formidable pathogen responsible for much morbidity and mortality worldwide, with disease being an exception rather than the rule. Expand
Kyoto global consensus report on Helicobacter pylori gastritis
TLDR
A global consensus for gastritis was developed for the first time, which will be the basis for an international classification system and for further research on the subject. Expand
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