IDE gene

Known as: INSULIN-DEGRADING ENZYME, IDE, INSULYSIN 
This gene is involved in the catabolism of insulin and other bioactive peptides.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2018
05010015019552017

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND A finding of reduced aortic-valve leaflet motion was noted on computed tomography (CT) in a patient who had a stroke… (More)
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Highly Cited
2013
Highly Cited
2013
Many threats present in smartphones are the result of interactions between application components, not just artifacts of single… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Genome-wide association studies have identified common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, HHEX/IDE, EXT2… (More)
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Highly Cited
2007
Highly Cited
2007
Type 2 diabetes mellitus results from the interaction of environmental factors with a combination of genetic variants, most of… (More)
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Highly Cited
2007
Highly Cited
2007
The molecular mechanisms involved in the development of type 2 diabetes are poorly understood. Starting from genome-wide genotype… (More)
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Highly Cited
2006
Highly Cited
2006
The thiazolidinediones, such as rosiglitazone, increase peripheral insulin sensitivity and their use is proposed for the… (More)
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Highly Cited
2003
Highly Cited
2003
Two substrates of insulin-degrading enzyme (IDE), amyloid beta-protein (Abeta) and insulin, are critically important in the… (More)
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Highly Cited
2003
Highly Cited
2003
Abeta is the major component of amyloid plaques characterizing Alzheimer's disease (AD). Abeta accumulation can be affected by… (More)
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Highly Cited
2000
Highly Cited
2000
Progressive cerebral accumulation of amyloid beta-protein (Abeta) is an early and invariant feature of Alzheimer's disease… (More)
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Highly Cited
1994
Highly Cited
1994
Cerebral deposition of beta-amyloid peptide (beta A) is a hallmark of Alzheimer's disease. Concentration of beta A could play a… (More)
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