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IDE gene

Known as: INSULIN-DEGRADING ENZYME, IDE, INSULYSIN 
This gene is involved in the catabolism of insulin and other bioactive peptides.
National Institutes of Health

Related topics

Related topics

5 relations
HydrolysisInsulinasePeptide MetabolismProteolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Examination of All Type 2 Diabetes GWAS Loci Reveals HHEX-IDE as a Locus Influencing Pediatric BMI
OBJECTIVE A number of studies have found that BMI in early life influences the risk of developing type 2 diabetes later in life… 
2003
2003
Oriented and vectorial immobilization of linear M13 dsDNA between interdigitated electrodes--towards single molecule DNA nanostructures.
Highly Cited
1998
Highly Cited
1998
Amyloidogenic determinant as a substrate recognition motif of insulin‐degrading enzyme
Highly Cited
1993
Highly Cited
1993
Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants.
Various xanthones as well as quercetin have been shown to exhibit antiplatelet activity. A series of anthraquinones analogues… 
Highly Cited
1993
Highly Cited
1993
The rat insulin‐degrading enzyme
Highly Cited
1991
Highly Cited
1991
Homologues of insulinase, a new superfamily of metalloendopeptidases.
On the basis of a statistical analysis of an alignment of the amino acid sequences, a new superfamily of metalloendopeptidases is… 
Highly Cited
1957
Highly Cited
1957
Insulinase-inhibitory Activity of Protein Hydrolysates.∗ †
Conclusion Destruction of insulin by extracts of rat liver is inhibited competitively by 3-hour acid hydrolysates and by tryptic… 
Highly Cited
1957
Highly Cited
1957
Insulinase, insulinase-inhibitors, and diabetes mellitus.
Highly Cited
1956
Highly Cited
1956
The inhibition of insulinase by hypoglycemic sulfonamides.
1956
1956
The role of insulinase and insulinase-inhibitors.
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