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ICI 198583

Known as: ICI-198583, ICI198583 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antineoplastic AgentsEnzyme InhibitorsFolic AcidFolic Acid Antagonists
analogs & derivatives

Papers overview

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2002
2002
Synthesis and biological activity of Na-[ 4-[ N-[ ( 3 , 4-dihydro-2-methyl-4-oxo-6-quinazolinyl ) methyl ]-N-propargylamino ] phenyl-acetyl ]-L-glutamic acid
2-Deamino-2-methyl-N 10 -propargyl-5,8-dideazafolic acid (ICI 198583) is a potent inhibitor of thymidylate synthase. Its analogue…