Hydroxysteroid Dehydrogenases

Known as: Dehydrogenases, Hydroxysteroid, Hydroxysteroid Dehydrogenases [Chemical/Ingredient], hydroxysteroid dehydrogenase 
Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.

Topic mentions per year

Topic mentions per year

1952-2017
010020030019522016

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Highly Cited
2004
Highly Cited
2004
The metabolic syndrome (visceral obesity, insulin resistance, type 2 diabetes, and dyslipidemia) resembles Cushing's Syndrome… (More)
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Highly Cited
2004
Highly Cited
2004
In obese humans and rodents there is increased expression of the key glucocorticoid (GC) regenerating enzyme, 11beta… (More)
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Highly Cited
2001
Highly Cited
2001
Excess tissue glucocorticoid action may underlie the dyslipidemia, insulin resistance, and impaired glucose tolerance of the… (More)
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Highly Cited
2001
Highly Cited
2001
The adverse metabolic consequences of obesity are best predicted by the quantity of visceral fat. Excess glucocorticoids produce… (More)
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Highly Cited
1997
Highly Cited
1997
Glucocorticoid hormones, acting via nuclear receptors, regulate many metabolic processes, including hepatic gluconeogenesis. It… (More)
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Highly Cited
1997
Highly Cited
1997
OBJECTIVE Placental 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD), which converts active cortisol to inactive cortisone, has… (More)
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Highly Cited
1996
Highly Cited
1996
Recent epidemiological studies have linked low birth weight with the later occurrence of cardiovascular and metabolic disorders… (More)
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Highly Cited
1994
Highly Cited
1994
The enzyme 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) is thought to protect the non-selective mineralocorticoid receptor… (More)
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Highly Cited
1988
Highly Cited
1988
In vitro the mineralocorticoid receptor is non-specific and does not distinguish between aldosterone and cortisol. In vivo… (More)
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Highly Cited
1987
Highly Cited
1987
The sodium retention associated with liquorice ingestion has been thought to be due to a direct mineralocorticoid effect, despite… (More)
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