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Hydroxysteroid Dehydrogenases

Known as: Dehydrogenases, Hydroxysteroid, Hydroxysteroid Dehydrogenases [Chemical/Ingredient], hydroxysteroid dehydrogenase 
Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (13)

11-beta-Hydroxysteroid Dehydrogenases17-Hydroxysteroid Dehydrogenases17-hydroxysteroid dehydrogenase3 (or 17)-beta-hydroxysteroid dehydrogenase

Broader (1)

Alcohol Oxidoreductases
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

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Review
2004
Review
2004
11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) interconverts inactive cortisone and active cortisol. Although… 
Highly Cited
2002
Highly Cited
2002
Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.
Cushing's syndrome and the metabolic syndrome share clinical similarities. Reports of alterations in the hypothalamic-pituitary… 
Highly Cited
2002
Highly Cited
2002
Critical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases*
Short-chain dehydrogenases/reductases form a large, evolutionarily old family of NAD(P)(H)-dependent enzymes with over 60 genes… 
Review
2000
Review
2000
Mutations in the NSDHL gene, encoding a 3beta-hydroxysteroid dehydrogenase, cause CHILD syndrome.
We report for the first time that CHILD syndrome (MIM 308050), an X-linked dominant, male-lethal trait characterized by an… 
Review
2000
Review
2000
Printed in U.S.A. Copyright © 2001 by The Endocrine Society Minireview: 11�-Hydroxysteroid Dehydrogenase Type 1— A Tissue-Specific Amplifier of Glucocorticoid Action*
  • 2000
  • Corpus ID: 2727904
Highly Cited
1997
Highly Cited
1997
11 b-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress
Glucocorticoid hormones, acting via nuclear receptors, regulate many metabolic processes, including hepatic gluconeogenesis. It… 
Highly Cited
1997
Highly Cited
1997
Placental 11β‐hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure
OBJECTIVE Placental 11β‐hydroxysteroid dehydrogenase (11β‐HSD), which converts active cortisol to inactive cortisone, has been… 
Highly Cited
1994
Highly Cited
1994
Cloning and tissue distribution of the human 1 lβ-hydroxysteroid dehydrogenase type 2 enzyme
Highly Cited
1988
Highly Cited
1988
Localisation of 11 beta-hydroxysteroid dehydrogenase--tissue specific protector of the mineralocorticoid receptor.
In vitro the mineralocorticoid receptor is non-specific and does not distinguish between aldosterone and cortisol. In vivo… 
Highly Cited
1987
Highly Cited
1987
MINERALOCORTICOID ACTIVITY OF LIQUORICE: 11-BETA-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY COMES OF AGE
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