11-beta-Hydroxysteroid Dehydrogenases

Known as: Dehydrogenase, 11beta-Hydroxysteroid, 11 beta Hydroxysteroid Dehydrogenases, Cortisone 11 Oxoreductase 
Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Lower activity of 11 beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2) classically induces hypertension by leading to… (More)
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Highly Cited
2005
Highly Cited
2005
Two isozymes of 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) interconvert active cortisol and inactive cortisone. 11 beta… (More)
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Highly Cited
2004
Highly Cited
2004
The enzyme 11 beta-hydroxysteroid dehydrogenase type 2 (11 beta HSD2) is selectively expressed in aldosterone target tissues… (More)
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Highly Cited
2004
Highly Cited
2004
The metabolic syndrome (visceral obesity, insulin resistance, type 2 diabetes, and dyslipidemia) resembles Cushing's Syndrome… (More)
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Highly Cited
1997
Highly Cited
1997
OBJECTIVE Placental 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD), which converts active cortisol to inactive cortisone, has… (More)
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Highly Cited
1996
Highly Cited
1996
OBJECTIVE Two isoforms of 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) catalyse the interconversion of cortisol to… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND It has been proposed that aldosterone exerts direct effects on heart function, most notably on the development of… (More)
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Highly Cited
1995
Highly Cited
1995
11 beta-Hydroxysteroid dehydrogenase (11 beta HSD) catalyzes the conversion of corticosterone to inert 11-dehydrocorticosterone… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Hyperandrogenemia is the hallmark of the polycystic ovary syndrome, yet the relative contributions of the adrenal… (More)
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Highly Cited
1988
Highly Cited
1988
We have proposed that 11 beta-hydroxysteroid dehydrogenase is composed of structurally independent units with 11 beta… (More)
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