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11-beta-hydroxysteroid dehydrogenase activity

Known as: corticosteroid 11-reductase, 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity, dehydrogenase, 11beta-hydroxy steroid 
Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+). [EC:1.1.1.146, PMID:15761036]
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Fetal glucocorticoid exposure is a key mechanism proposed to underlie prenatal "programming" of adult cardiometabolic and… Expand
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Highly Cited
2005
Highly Cited
2005
This study investigated the effects of acute and chronic restraint stress during the third week of pregnancy on placental 11beta… Expand
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Review
2005
Review
2005
Two isozymes of 11beta-hydroxysteroid dehydrogenase (11beta-HSD1 and 11beta-HSD2) catalyse the interconversion of hormonally… Expand
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Review
2004
Review
2004
Epidemiological evidence suggests that low birth weight is associated with an increased risk of cardiovascular, metabolic and… Expand
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Highly Cited
2003
Highly Cited
2003
Asthma during pregnancy is associated with a low birth weight, although the mechanisms contributing to this outcome remain… Expand
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Review
2002
Review
2002
Increased uterine contractility at term and preterm results first from activation and then stimulation of the myometrium… Expand
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Highly Cited
2001
Highly Cited
2001
Cortisol has been implicated as a pathophysiological mediator in idiopathic obesity, but circulating cortisol concentrations are… Expand
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Highly Cited
2001
Highly Cited
2001
Excess tissue glucocorticoid action may underlie the dyslipidemia, insulin resistance, and impaired glucose tolerance of the… Expand
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Highly Cited
2000
Highly Cited
2000
Glucocorticoids may underlie the association between prenatal stress, low birth weight and adult stress-associated disorders, e.g… Expand
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Review
2000
Review
2000
Epidemiological studies in many distinct human populations have associated low weight or thinness at birth with a substantially… Expand
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